The glycosylation defect in solute carrier SLC35A2/SLC35A3 double knockout cells is rescued by SLC35A2–SLC35A3 and SLC35A3–SLC35A2 hybrids

W Wiertelak, A Pavlovskyi… - FEBS …, 2023 - Wiley Online Library
SLC35A2 and SLC35A3 are homologous proteins with postulated nucleotide sugar
transporting activities. Unlike SLC35A2, whose specificity for UDP‐Gal is well‐established …

SLC35A5 Protein—A Golgi complex member with putative nucleotide sugar transport activity

P Sosicka, B Bazan, D Maszczak-Seneczko… - International Journal of …, 2019 - mdpi.com
Solute carrier family 35 member A5 (SLC35A5) is a member of the SLC35A protein
subfamily comprising nucleotide sugar transporters. However, the function of SLC35A5 is …

[HTML][HTML] Identification of novel potential interaction partners of UDP-galactose (SLC35A2), UDP-N-acetylglucosamine (SLC35A3) and an orphan (SLC35A4) …

M Wiktor, W Wiertelak, D Maszczak-Seneczko… - Journal of …, 2021 - Elsevier
Nucleotide sugar transporters (NSTs) are ER and Golgi-resident members of the solute
carrier 35 (SLC35) family which supply substrates for glycosylation by exchanging lumenal …

Biosynthesis of GlcNAc-rich N-and O-glycans in the Golgi apparatus does not require the nucleotide sugar transporter SLC35A3

B Szulc, P Sosicka, D Maszczak-Seneczko… - Journal of Biological …, 2020 - ASBMB
Nucleotide sugar transporters, encoded by the SLC35 gene family, deliver nucleotide
sugars throughout the cell for various glycosyltransferase-catalyzed glycosylation reactions …

[HTML][HTML] An insight into the orphan nucleotide sugar transporter SLC35A4

P Sosicka, D Maszczak-Seneczko, B Bazan… - … et Biophysica Acta (BBA …, 2017 - Elsevier
SLC35A4 has been classified in the SLC35A subfamily based on amino acid sequence
homology. Most of the proteins belonging to the SLC35 family act as transporters of …

Lysine at position 329 within a C-terminal dilysine motif is crucial for the ER localization of human SLC35B4

B Bazan, M Wiktor, D Maszczak-Seneczko, T Olczak… - PLoS …, 2018 - journals.plos.org
SLC35B4 belongs to the solute carrier 35 (SLC35) family whose best-characterized
members display a nucleotide sugar transporting activity. Using an experimental model of …

Residence of the Nucleotide Sugar Transporter Family Members SLC35F1 and SLC35F6 in the Endosomal/Lysosomal Pathway

F Van den Bossche, V Tevel, F Gilis… - International Journal of …, 2024 - mdpi.com
The SLC35 (Solute Carrier 35) family members acting as nucleotide sugar transporters are
typically localized in the endoplasmic reticulum or Golgi apparatus. It is, therefore, intriguing …

[PDF][PDF] Subcellular localization of UDP-GlcNAc, UDP-Gal and SLC35B4 transporters

D Maszczak-Seneczko, T Olczak… - Acta Biochimica …, 2011 - frontierspartnerships.org
The mechanisms of transport and distribution of nucleotide sugars in the cell remain unclear.
In an attempt to further characterize nucleotide sugar transporters (NSTs), we determined …

SLC35A2 Deficiency Promotes an Epithelial-to-Mesenchymal Transition-like Phenotype in Madin–Darby Canine Kidney Cells

M Kot, E Mazurkiewicz, M Wiktor, W Wiertelak… - Cells, 2022 - mdpi.com
In mammalian cells, SLC35A2 delivers UDP–galactose for galactosylation reactions that
take place predominantly in the Golgi lumen. Mutations in the corresponding gene cause a …

[HTML][HTML] SLC35A2 deficiency reduces protein levels of core 1 β-1, 3-galactosyltransferase 1 (C1GalT1) and its chaperone Cosmc and affects their subcellular …

W Wiertelak, K Chabowska, B Szulc… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Nucleotide sugar transporters (NSTs) are multitransmembrane proteins, localized in the
Golgi apparatus and/or endoplasmic reticulum, which provide glycosylation enzymes with …