Non‐coding RNA‐associated competitive endogenous RNA regulatory networks: novel diagnostic and therapeutic opportunities for hepatocellular carcinoma

S Khashkhashi Moghadam… - Journal of cellular …, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC), as the most prevalent liver malignancy, is annually
diagnosed in more than half a million people worldwide. HCC is strongly associated with …

[HTML][HTML] Epigenetic associations between lncRNA/circRNA and miRNA in hepatocellular carcinoma

TS Han, K Hur, HS Cho, HS Ban - Cancers, 2020 - mdpi.com
Simple Summary Non-coding RNAs such as microRNAs, long non-coding RNAs, and
circular RNAs contribute to the development and progression of hepatocellular carcinoma …

[HTML][HTML] Differentially expressed non-coding RNAs and their regulatory networks in liver cancer

NT Moldogazieva, SP Zavadskiy, DV Astakhov… - Heliyon, 2023 - cell.com
The vast majority of human transcriptome is represented by various types of small RNAs with
little or no protein-coding capability referred to as non-coding RNAs (ncRNAs). Functional …

[HTML][HTML] The role of competing endogenous RNA network in the development of hepatocellular carcinoma: potential therapeutic targets

Z Tang, X Li, Y Zheng, J Liu, C Liu, X Li - Frontiers in Cell and …, 2024 - frontiersin.org
The current situation of hepatocellular carcinoma (HCC) management is challenging due to
its high incidence, mortality, recurrence and metastasis. Recent advances in gene genetic …

[HTML][HTML] Non-coding RNAs in hepatocellular carcinoma: Insights into regulatory mechanisms, clinical significance, and therapeutic potential

Q Han, M Wang, X Dong, F Wei, Y Luo… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is a complex and heterogeneous malignancy with high
incidence and poor prognosis. In addition, owing to the lack of diagnostic and prognostic …

[HTML][HTML] Role of long noncoding RNA-mediated competing endogenous RNA regulatory network in hepatocellular carcinoma

ZS Niu, WH Wang, XN Dong - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) are noncoding RNAs
(ncRNAs) that occupy over 90% of the human genome, and their main function is to directly …

Competing Endogenous RNAs in Hepatocellular Carcinoma—The Pinnacle of Rivalry

AY Afify, SA Ibrahim, MH Aldamsisi… - Seminars in liver …, 2019 - thieme-connect.com
The role of noncoding transcripts in gene expression is nowadays acknowledged to keep
various diseases at bay—despite being referred to as “junk” DNA several years ago …

Decoding hepatocarcinogenesis from a noncoding RNAs perspective

MKA El‐Aziz, A Dawoud, CJ Kiriacos… - Journal of cellular …, 2023 - Wiley Online Library
Being a leading lethal malignancy worldwide, the pathophysiology of hepatocellular
carcinoma (HCC) has gained a lot of interest. Yet, underlying mechanistic basis of the liver …

[HTML][HTML] Construction of a ceRNA regulatory network to explore potential pathogenesis mechanisms involved in human hepatocellular carcinoma

Y Liu, Z Dong, WJ Chen, L Chen, L Ju, W Cai, X Luo… - Scientific Reports, 2023 - nature.com
Worldwide, primary liver cancer is the third leading cause of cancer-related death.
Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers. Recent …

[HTML][HTML] The emerging roles of non-coding competing endogenous RNA in hepatocellular carcinoma

G Xu, WY Xu, Y Xiao, B Jin, SD Du, Y Mao… - Cancer Cell …, 2020 - Springer
Accumulating evidence has emerged revealing that noncoding RNAs (ncRNAs) play
essential roles in the occurrence and development of hepatocellular carcinoma (HCC) …