Next generation sequencing

M Le Mercier, N D'Haene, S Rorive… - Revue Medicale de …, 2016 - europepmc.org
Fine needle aspiration is the gold standard method to differentiate benign thyroid nodules
from malignant. However, for 15 to 30% of the cases the cytological diagnosis is …

Molecular diagnosis for indeterminate thyroid nodules on fine needle aspiration: advances and limitations

XM Keutgen, F Filicori, TJ Fahey III - Expert review of molecular …, 2013 - Taylor & Francis
Indeterminate thyroid lesions are diagnosed in up to 30% of fine needle aspirations. These
nodules harbor malignancy in more than 25% of cases, and hemithyroidectomy or total …

New strategies in diagnosing cancer in thyroid nodules: impact of molecular markers

YE Nikiforov, L Yip, MN Nikiforova - Clinical cancer research, 2013 - AACR
Thyroid cancer is the most common type of endocrine malignancy, with approximately
55,000 new cases diagnosed in the United States in 2012. However, thyroid nodules are …

The quest for diagnostic molecular markers for thyroid nodules with indeterminate or suspicious cytology

G Kouniavsky, MA Zeiger - Journal of surgical oncology, 2012 - Wiley Online Library
Thyroid nodules are very common and fine needle aspiration (FNA) is a very sensitive
means of diagnosis. However, its limitations include the fact that the cytology reports are …

Thyroid and molecular testing. Advances in thyroid molecular cytopathology

ED Rossi, P Vielh - Journal of Molecular Pathology, 2021 - mdpi.com
Thyroid nodules are a common finding in the adult population including the fact that more
than 50% of individuals, over the age of 60, have thyroid nodules. The majority have been …

[HTML][HTML] Differential diagnosis of thyroid nodules using fine-needle aspiration cytology and oncogene mutation screening: are we ready?

RM Melillo, M Santoro, G Vecchio - F1000 medicine reports, 2010 - ncbi.nlm.nih.gov
Thyroid nodules are a very common clinical finding, and although the majority of them are
benign, thyroid carcinoma accounts for about 5-15% of nodules. Fine-needle aspiration …

Molecular diagnostics for thyroid nodules: the current state of affairs

SY Mon, SP Hodak - Endocrinology and Metabolism Clinics, 2014 - endo.theclinics.com
Fine-needle aspiration (FNA) cytology remains the gold standard for the evaluation of
thyroid nodules. However, 10% to 40% of thyroid FNAs are cytologically indeterminate. 1 …

Molecular testing of thyroid fine-needle aspiration: Local issues and solutions. An interventional cytopathologist perspective

C Bellevicine, R Sgariglia, M Nacchio… - Journal of Molecular …, 2021 - mdpi.com
Molecular testing has acquired a relevant role for diagnostic and prognostic stratification of
indeterminate thyroid nodules. Besides the available commercial solutions marketed in the …

B-392 Standardization of Nucleic acid Extraction Method From Thyroid Fine Needle Aspiration (FNA) Cells on Stained and Fixed Slides for Next-Generation …

LA Martins, RS Domingues, GM de Moraes… - Clinical …, 2023 - academic.oup.com
Abstract Background Thyroid Fine Needle Aspiration (FNA) cytopathology is the best
method for histological classification of thyroid nodules. However, between 20%–30% of …

Value of molecular tests in cytologically indeterminate lesions of thyroid

X Zhang - Archives of pathology & laboratory medicine, 2015 - meridian.allenpress.com
Context Fine-needle aspiration has been the initial step in the workup of thyroid nodular
lesions and has successfully reduced the number of unnecessary surgeries and improved …