LncRNA as a therapeutic target for angiogenesis
Background: Out of 3 billion base pairs in human genome only~ 2% code for proteins; and
out of 180,000 transcripts in human cells, about 20,000 code for protein, remaining 160,000 …
out of 180,000 transcripts in human cells, about 20,000 code for protein, remaining 160,000 …
MALAT1 — a paradigm for long noncoding RNA function in cancer
T Gutschner, M Hämmerle, S Diederichs - Journal of molecular medicine, 2013 - Springer
The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a bona fide long
noncoding RNA (lncRNA). MALAT1, also known as nuclear-enriched transcript 2 (NEAT2) …
noncoding RNA (lncRNA). MALAT1, also known as nuclear-enriched transcript 2 (NEAT2) …
Long noncoding RNA MALAT1: insights into its biogenesis and implications in human disease
Genome-wide studies have identified thousands of noncoding RNAs (ncRNAs) with no
protein coding capacity. Among them, the long non-coding RNAs (lncRNAs), which are more …
protein coding capacity. Among them, the long non-coding RNAs (lncRNAs), which are more …
Long noncoding RNAs in atherosclerosis and vascular injury: pathobiology, biomarkers, and targets for therapy
JB Pierce, MW Feinberg - Arteriosclerosis, thrombosis, and …, 2020 - Am Heart Assoc
Despite major advances in the primary and secondary prevention of atherosclerosis and its
risk factors, atherosclerotic cardiovascular disease remains a major clinical and financial …
risk factors, atherosclerotic cardiovascular disease remains a major clinical and financial …
The role of lncRNA MALAT1 in cardiovascular disease
Y Yan, D Song, X Song, C Song - IUBMB life, 2020 - Wiley Online Library
Cardiovascular disease (CVD) is the first leading cause of death worldwide. Understanding
the molecular mechanism of signaling pathways involved in pathology of CVD is benefit for …
the molecular mechanism of signaling pathways involved in pathology of CVD is benefit for …
Identification and initial functional characterization of a human vascular cell–enriched long noncoding RNA
RD Bell, X Long, M Lin, JH Bergmann… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Long noncoding RNAs (lncRNAs) represent a rapidly growing class of RNA
genes with functions related primarily to transcriptional and post-transcriptional control of …
genes with functions related primarily to transcriptional and post-transcriptional control of …
Mechanisms of lncRNA/microRNA interactions in angiogenesis
Z Zhao, W Sun, Z Guo, J Zhang, H Yu, B Liu - Life sciences, 2020 - Elsevier
Angiogenesis is a complex physiological process. However, over the past couple of
decades, abnormally accelerated or pathological angiogenesis has garnered greater …
decades, abnormally accelerated or pathological angiogenesis has garnered greater …
Long noncoding RNA Malat1 regulates cerebrovascular pathologies in ischemic stroke
The study was designed to determine the role of long noncoding RNA (lncRNA), metastasis-
associated lung adenocarcinoma transcript 1 (Malat1), in ischemic stroke outcome. Primary …
associated lung adenocarcinoma transcript 1 (Malat1), in ischemic stroke outcome. Primary …
[HTML][HTML] Long noncoding RNAs in key cellular processes involved in aortic aneurysms
Aortic aneurysm (AA) is a complex and dangerous vascular disease, featuring progressive
and irreversible vessel dilatation. AA is typically detected either by screening, or identified …
and irreversible vessel dilatation. AA is typically detected either by screening, or identified …
lncRNA/MicroRNA interactions in the vasculature
MD Ballantyne, RA McDonald… - Clinical Pharmacology & …, 2016 - Wiley Online Library
MicroRNA (miRNA) have gained widespread attention for their role in diverse vascular
processes including angiogenesis, apoptosis, proliferation, and migration. Despite great …
processes including angiogenesis, apoptosis, proliferation, and migration. Despite great …