The endothelial lining can be viewed as the first line of defense against risk factors of
vascular disease. Endothelial dysfunction is regarded as an initial event for atherogenesis …

Hypertension (HTN) or high blood pressure is a predominant noncommunicable disease in
the developing and developed world [1–3]. The incidence of HTN has increased rapidly over …

Objective: Despite the current antiatherosclerotic and antithrombotic therapies, the incidence
of advanced atherosclerosis-associated clinical events remains high. Whether long …

Chronic metabolic disorders such as obesity and diabetes are associated with accelerated
rates of macrovascular and microvascular complications, which are leading causes of …

Long non-coding RNAs (lncRNAs) interact with the nuclear architecture and are involved in
fundamental biological mechanisms, such as imprinting, histone-code regulation, gene …

Following completion of the human genome, it became evident that the majority of our DNA
is transcribed into non-coding RNAs (ncRNAs) instead of protein-coding messenger RNA …

Melanoma is the most lethal cutaneous cancer with a highly aggressive and metastatic
phenotype. While recent genetic and epigenetic studies have shed new insights into the …

Non-coding RNAs are emerging as regulatory RNAs that participate in the regulation of
gene expression and play vital roles in various biological and pathological processes. Long …

Long non-coding RNAs (lncRNAs) have emerged as critical regulators in human disease
including atherosclerosis. However, the mechanisms involved in the post-transcriptional …

The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …