Environmental estrogens suppress hormones, behavior, and reproductive fitness in male fathead minnows

D Martinović, WT Hogarth, RE Jones… - … and Chemistry: An …, 2007 - Wiley Online Library
This study explored the possibility that environmental estrogens in sewage effluent may
reduce the reproductive fitness of adult male fish by suppressing their reproductive …

Zebrafish (Danio rerio) as a model organism for investigating endocrine disruption

H Segner - Comparative Biochemistry and Physiology Part C …, 2009 - Elsevier
Endocrine-disrupting compounds (EDCs) are widespread in the aquatic environment and
can cause alterations in development, physiological homeostasis and health of vertebrates …

Widespread sexual disruption in wild fish

S Jobling, M Nolan, CR Tyler, G Brighty… - … science & technology, 1998 - ACS Publications
A number of chemicals present in the environment have been shown to mimic or antagonize
the actions of steroid hormones, an issue often described as “endocrine …

Re-evaluating the significance of estrone as an environmental estrogen

GT Ankley, D Feifarek, B Blackwell… - … science & technology, 2017 - ACS Publications
Studies worldwide have demonstrated the occurrence of feminized male fish at sites
impacted by human and animal wastes. A variety of chemicals could contribute to this …

Development and recovery of histopathological alterations in the gonads of zebrafish (Danio rerio) after single and combined exposure to endocrine disruptors (17α …

A Luzio, SM Monteiro, E Rocha… - Aquatic Toxicology, 2016 - Elsevier
Exposure of wildlife to endocrine disrupting chemicals (EDCs) is not necessarily continuous.
Due to seasonal changes and variable industrial and agricultural activities it often occurs …

Life-stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure

G Maack, H Segner - Comparative Biochemistry and Physiology Part C …, 2004 - Elsevier
The aim of this study was to identify periods in zebrafish (Danio rerio) development when
estrogen exposure has long-term consequences on reproductive capabilities at the adult …

[HTML][HTML] Long-term exposure to low 17α-ethinylestradiol (EE2) concentrations disrupts both the reproductive and the immune system of juvenile rainbow trout …

K Rehberger, EW von Siebenthal, C Bailey… - Environment …, 2020 - Elsevier
Estrogenic endocrine disrupting compounds (EEDCs), such as ethinylestradiol (EE2), are
well studied for their impact on the reproductive system of fish. EEDCs may also impact the …

Endocrine disruption: why is it so complicated?

AL Lister, GJ Van Der Kraak - Water Quality Research Journal, 2001 - iwaponline.com
The intricate nature of the vertebrate endocrine system creates several challenges that
impede the understanding of the threats that endocrine disrupting substances (EDS) may …

Accurate prediction of the response of freshwater fish to a mixture of estrogenic chemicals

JV Brian, CA Harris, M Scholze… - Environmental …, 2005 - ehp.niehs.nih.gov
Existing environmental risk assessment procedures are limited in their ability to evaluate the
combined effects of chemical mixtures. We investigated the implications of this by analyzing …

Reproductive and developmental effects of endocrine disrupters in invertebrates: in vitro and in vivo approaches

TH Hutchinson - Toxicology letters, 2002 - Elsevier
In order to gain basic understanding in the ecotoxicity of endocrine disrupting chemicals or
EDCs (including natural chemicals and some pharmaceuticals), many international research …