GAS5 inhibits gastric cancer cell proliferation partly by modulating CDK6

X Guo, K Deng, H Wang, J Xia, T Shan… - Oncology research and …, 2015 - karger.com
Introduction: As it is not clear whether growth arrest-specific 5 (GAS5) inhibits gastric cancer
(GC) cell proliferation by regulating cell cycle, we analyzed the effect of GAS5 on cell cycle …

Downregulation of gas5 increases pancreatic cancer cell proliferation by regulating CDK6

X Lu, Y Fang, Z Wang, J Xie, Q Zhan, X Deng… - Cell and tissue …, 2013 - Springer
Recent studies have revealed that long non-coding RNAs (lncRNAs) play important roles in
cancer biology and that lncRNA gas5 (growth arrest-specific 5) regulates breast cancer cell …

Growth arrest‐specific gene 1 is downregulated and inhibits tumor growth in gastric cancer

H Wang, X Zhou, Y Zhang, H Zhu, L Zhao… - The FEBS …, 2012 - Wiley Online Library
Gastric cancer is one of the leading causes of malignancy‐related mortality in the world, and
malignant growth is a crucial characteristic in gastric cancer. In our previous study, we found …

The GAS5/miR-222 axis regulates proliferation of gastric cancer cells through the PTEN/Akt/mTOR pathway

Y Li, J Gu, H Lu - Digestive diseases and sciences, 2017 - Springer
Background Several lines of evidence have indicated that growth arrest-specific transcript 5
(GAS5) functions as a tumor suppressor and is aberrantly expressed in multiple cancers …

Growth arrest‐specific gene 6 and Axl signaling enhances gastric cancer cell survival via Akt pathway

T Sawabu, H Seno, T Kawashima… - … in cooperation with …, 2007 - Wiley Online Library
Activation of tyrosine kinases is an important factor during cancer development. Axl, one of
the receptor tyrosine kinases, binds to the specific ligand growth arrest‐specific gene 6 …

GAS5 is downregulated in gastric cancer cells by promoter hypermethylation and regulates adriamycin sensitivity.

N Zhang, AY Wang, XK Wang… - European Review for …, 2016 - search.ebscohost.com
OBJECTIVE: GAS5 is a tumor suppressive lncRNA that is downregulated in gastric cancer.
In this study, we firstly investigated whether epigenetic regulation contributed to GAS5 …

Gas1 Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma

Q Li, Y Qin, P Wei, P Lian, Y Li, Y Xu, X Li, D Li… - Molecular Cancer …, 2016 - AACR
Abstract Growth arrest–specific 1 (Gas1) plays a critical role in growth suppression. Previous
study indicated that Gas1 was closely associated with survival in patients with colorectal …

GAS5‑mediated regulation of cell signaling

Y Zhou, B Chen - Molecular medicine reports, 2020 - spandidos-publications.com
In recent years, an increasing number of long non‑coding RNAs (lncRNAs) have been
discovered using microarrays and nucleic acid sequencing technology. LncRNAs exert …

Gas7 attenuates hepatocellular carcinoma progression and chemoresistance through the PI3K/Akt signaling pathway

WF Liu, QW Zhang, B Quan, F Zhang, M Li, SX Lu… - Cellular …, 2023 - Elsevier
Growth arrest-specific gene 7 (Gas7) was involved in various cellular functions, although its
specific roles and molecular mechanisms in hepatocellular carcinoma (HCC) remained …

[HTML][HTML] Data on clinical significance of GAS2 in colorectal cancer cells

CC Chang, CC Huang, SH Yang, CC Chien, CL Lee… - Data in brief, 2016 - Elsevier
The growth arrest-specific 2 (GAS2) was cloned and found to be upregulated in the feces of
recurrent CRC patients. This overexpressed GAS2 induced different patterns of gene …