Selecting GLP-1 agonists in the management of type 2 diabetes: differential pharmacology and therapeutic benefits of liraglutide and exenatide

J Pinkney, T Fox, L Ranganath - Therapeutics and clinical risk …, 2010 - Taylor & Francis
Failure of secretion of the incretin hormone glucagon-like peptide-1 (GLP-1) plays a
prominent role in type 2 diabetes, and restoration of GLP-1 action is an important therapeutic …

The safety and tolerability of GLP‐1 receptor agonists in the treatment of type‐2 diabetes

D Russell‐Jones - International journal of clinical practice, 2010 - Wiley Online Library
Established therapies for type‐2 diabetes effectively reduce blood glucose, but are often
associated with adverse effects that pose risks to patient's health or diminish adherence to …

Glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized clinical trials

M Monami, N Marchionni… - European journal of …, 2009 - academic.oup.com
Objective The role of glucagon-like peptide-1 (GLP-1) receptor agonists in the treatment of
type 2 diabetes is debated; many recent trials, which were not included in previous meta …

Emerging GLP-1 receptor agonists

A Lund, FK Knop, T Vilsbøll - Expert opinion on emerging drugs, 2011 - Taylor & Francis
Introduction: Recently, glucagon-like peptide-1 receptor (GLP-1R) agonists have become
available for the treatment of type 2 diabetes. These agents exploit the physiological effects …

Glucagon-like peptide-1 analogues for Type 2 diabetes mellitus: current and emerging agents

B Gallwitz - Drugs, 2011 - Springer
Novel therapeutic options for type 2 diabetes mellitus based on the action of the incretin
hormone glucagon-like peptide (GLP)-1 were introduced in 2005. As injectable GLP-1 …

Glucagon-like peptide-1 (GLP-1) receptor agonists: Differentiating the new medications

JR Unger, CG Parkin - Diabetes Therapy, 2011 - Springer
Abstract Introduction Glucagon-like peptide-1 (GLP-1) has been the focus of considerable
research activity in the treatment of type 2 diabetes mellitus (T2DM) because the incretin …

Novel GLP-1 receptor agonists for diabetes

AJ Garber - Expert opinion on investigational drugs, 2012 - Taylor & Francis
Introduction: GLP-1 receptor agonists have been shown to be effective in the treatment of
type 2 diabetes mellitus (T2DM). Although the first GLP-1 receptor agonist, exenatide, was …

A comparison of currently available GLP-1 receptor agonists for the treatment of type 2 diabetes

E Montanya - Expert opinion on pharmacotherapy, 2012 - Taylor & Francis
Introduction: Glucagon-like peptide-1 (GLP-1) receptor agonists are a valuable addition to
the type 2 diabetes armamentarium. They increase insulin secretion and reduce glucagon …

GLP-1 agonists for type 2 diabetes: pharmacokinetic and toxicological considerations

MJ Jespersen, FK Knop… - Expert opinion on drug …, 2013 - Taylor & Francis
Introduction: Within recent years, glucagon-like peptide 1 receptor agonists (GLP-1-RA)
have emerged as a new treatment option for type 2 diabetes. The GLP-1-RA are …

[HTML][HTML] A plethora of GLP-1 agonists: decisions about what to use and when

SL Samson, AJ Garber - Current diabetes reports, 2016 - Springer
Incretin-based therapies are important addition to our armamentarium for the treatment of
type 2 diabetes (T2DM). There are six Glucagon-like peptide-1 receptor agonists (GLP …