During the last 15–20 years the general problem of pharmacokinetic drug interactions has
received increasing attention. Over this period a number of new and unique classes of …

During the last 20 years, the general problem of pharmacokinetic drug interactions has
received increasing attention. Over this period a number of new and unique classes of …

Drugs may frequently interact adversely to cause drug toxicity or render a needed therapy
ineffective. The situation is compounded by the current pattern of drug usage in which …

Few topics in clinical medicine have attracted more attention during the past decade than
undesirable interactions between pharmacotherapeutic agents administered concomitantly …

Drug Drug Interactions is a comprehensive review of the scientific and regulatory
perspectives of drug drug interactions from the point-of-view of academia, industry, and …

The potential number of drug interactions increases with each release of a new drug onto
the market. Each new agent has the theoretical potential to interact with all those that …

Interactions between drugs were first recognized over 100 years ago. A drug interaction is
said to occur when the response of a patient to a drug is changed by the presence of …

Physicians can predict the way in which many drugs will interact if they differentiate between
acidic and basic drugs and learn a few pharmacokinetic processes common to all drugs …

Interactions between drugs may result in favorable, toxic or no clinical effects. Generally
classified in terms of proposed mechanism, drug interactions may be causal to …