A drug-drug interaction (DDI) can result from changes in the pharmacokinetics (PK) of a drug
and/or its metabolites due to alteration in absorption, distribution, metabolism, and/or …

Drug interactions are important causes of both unexpected toxic and therapeutic effects.
Adverse reactions due to drug interaction are proportional to the number of drugs given and …

The characteristics of disease-drug interactions differ from those of drug-drug interaction or
food-drug interaction in that the former is much more variable than the latter two. Because …

Drug interactions in patients receiving multiple drug regimens are a constant concern for the
clinician. With the increased availability of new drugs and their concomitant use with other …

Publisher Summary With the increasing median age of the population, and the now known
effectiveness of multiple-therapy regimens for viral diseases, for example, HIV, cancer …

The potential importance of drug-drug interaction (DDIs) is increasing as polypharmacy
becomes more and more prevalent. In vitro data cannot directly predict clinical DDIs, but …

Newly approved drugs expand our therapeutic armamentarium, but augment the potential
for drug–drug interactions. These can be broadly categorized into pharmaceutical …

Pharmacokinetics literally means 'movement of drugs inside the body'and is concerned with
the fate of drugs administered to an organism. Thus, the study of drug absorption …