A large number of drugs are introduced every year, and new interactions between
medications are increasingly reported. Consequently, it is no longer practical for physicians …

Every time a drug is administered with any other prescription medicine, OTC products, herbs
or even food we expose ourselves to the risk of a potentially dangerous interaction …

HOW CAN DRUG INTERACTION OCCUR? Drug interaction may be a direct effect of one
compound upon another, by modification of intestinal absorption, by affecting the transport of …

Open any current medical journal and one is reminded that the coadministration of two or
more drugs can either cause deleterious effects or lead to ineffective therapy. Those …

The effects of one drug can be increased or decreased by the previous or concurrent
administration of another drug. Drug interactions are a particular problem because of the …

Reports on pharmacokinetic drug–drug interaction studies account for a major fraction of
manuscripts in clinical pharmacology journals; this issue of European Journal of Clinical …

This chapter lays down the conceptual framework for understanding the quantitative and
temporal aspects of drug-drug interactions, hereafter called drug interactions for simplicity …

In the past, there was a tendency to prescribe several drugs, either in combination or
separately, in the search of Combinations that would be less toxic or more effective than any …

Interactions between drugs were first recognised over 100 years ago. A drug interaction is
said to occur when the response of a patient to a drug is changed by the presence of …

A drug‐drug interaction (DDI) occurs when one or more drugs affect the pharmacokinetics
(the body's effect on the drug) and/or pharmacodynamics (the drug's effect on the body) of …