A mass spectrometric method to simultaneously measure a biomarker and dilution marker in exhaled breath condensate

CR Esther Jr, HM Jasin, LB Collins… - … Journal Devoted to …, 2008 - Wiley Online Library
Exhaled breath condensate (EBC) collection is a simple and non‐invasive method to
sample airway secretions, but analysis is limited by extensive and variable dilution of airway …

Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis

CR Esther Jr, G Boysen, BM Olsen… - … of Physiology-Lung …, 2009 - journals.physiology.org
Exhaled breath condensate (EBC) analyses promise simple and noninvasive methods to
measure airway biomarkers but pose considerable methodological challenges. We utilized …

Determining the presence of asthma-related molecules and salivary contamination in exhaled breath condensate

C Cruickshank-Quinn, M Armstrong, R Powell… - Respiratory …, 2017 - Springer
Background Researchers investigating lung diseases, such as asthma, have questioned
whether certain compounds previously reported in exhaled breath condensate (EBC) …

Determining urea levels in exhaled breath condensate with minimal preparation steps and classic LC–MS

M Pitiranggon, MS Perzanowski… - Journal of …, 2014 - academic.oup.com
Exhaled breath condensate (EBC) provides a relatively easy, non-invasive method for
measuring biomarkers of inflammation and oxidative stress in the airways. However, the …

Bioanalysis of underivatized amino acids in non-invasive exhaled breath condensate samples using liquid chromatography coupled with tandem mass spectrometry

L Konieczna, M Pyszka, M Okońska… - … of Chromatography A, 2018 - Elsevier
Exhaled breath condensate (EBC) is receiving increased attention as a novel, entirely non-
invasive technique for collecting biomarker samples. This increased attention is due to the …

Advances in proteomics methods for the analysis of exhaled breath condensate

EJ Yoo, JS Kim, S Stransky, S Spivack… - Mass Spectrometry …, 2024 - Wiley Online Library
The analysis of exhaled breath condensate (EBC) demonstrates a promising avenue of
minimally invasive biopsies for diagnostics. EBC is obtained by cooling exhaled air and …

Exhaled breath condensate: methodological recommendations and unresolved questions

I Horváth, J Hunt, PJ Barnes - European Respiratory Journal, 2005 - Eur Respiratory Soc
Collection of exhaled breath condensate (EBC) is a noninvasive method for obtaining
samples from the lungs. EBC contains large number of mediators including adenosine …

Exhaled breath condensate: a promising source for biomarkers of lung disease

Y Liang, SM Yeligar, LAS Brown - The Scientific World Journal, 2012 - Wiley Online Library
Exhaled breath condensate (EBC) has been increasingly studied as a noninvasive research
method for sampling the alveolar and airway space and is recognized as a promising source …

Exhaled breath condensate for proteomic biomarker discovery

SW Harshman, CC Grigsby, DK Ott - Chromatography, 2014 - mdpi.com
Exhaled breath condensate (EBC) has been established as a potential source of respiratory
biomarkers. Compared to the numerous small molecules identified, the protein content of …

Method optimization and validation for the simultaneous determination of arachidonic acid metabolites in exhaled breath condensate by liquid chromatography …

LM Gonzalez-Reche, AK Musiol, A Müller-Lux… - Journal of Occupational …, 2006 - Springer
Background Determinations of inflammatory markers in exhaled breath condensate were
used to assess airway inflammation. The most applied method for this kind of determination …