Therapeutic effect of baicalin on inflammatory bowel disease: A review

X Wang, L Xie, J Long, K Liu, J Lu, Y Liang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Baicalin (BI) is an important biologically active flavonoid
isolated from the root of Scutellaria radix (Huang Qin). Traditionally Scutellaria radix was the …

[HTML][HTML] The comparative study of the therapeutic effects and mechanism of baicalin, baicalein, and their combination on ulcerative colitis rat

S Liang, X Deng, L Lei, Y Zheng, J Ai, L Chen… - Frontiers in …, 2019 - frontiersin.org
Introduction: Ulcerative colitis (UC) is an inflammatory bowel disease with a high incidence
rate and a difficult treatment regimen. Recently, significant advances in the treatment of …

[HTML][HTML] Role of baicalin as a potential therapeutic agent in hepatobiliary and gastrointestinal disorders: A review

R Ganguly, A Gupta, AK Pandey - World journal of …, 2022 - ncbi.nlm.nih.gov
Baicalin is a natural bioactive compound derived from Scutellaria baicalensis, which is
extensively used in traditional Chinese medicine. A literature survey demonstrated the broad …

Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects

Q Hu, W Zhang, Z Wu, X Tian, J Xiang, L Li, Z Li… - Pharmacological …, 2021 - Elsevier
With the development of high-throughput screening and bioinformatics technology, natural
products with a range of pharmacological targets in multiple diseases have become …

[HTML][HTML] The role of intestinal microflora in anti-inflammatory effect of baicalin in mice

MA Jung, SE Jang, SW Hong, MJ Hana… - Biomolecules & …, 2012 - ncbi.nlm.nih.gov
Baicalin, a main constituent of the rhizome of Scutellaria baicalensis, is metabolized to
baicalein and oroxylin A in the intestine before its absorption. To understand the role of …

[HTML][HTML] Baicalin down regulates the expression of TLR4 and NFkB-p65 in colon tissue in mice with colitis induced by dextran sulfate sodium

J Feng, C Guo, Y Zhu, L Pang, Z Yang… - … Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
Background: Baicalin is one of flavonoid extracts from Scutellaria baicalensis, which has
several functions including anti-inflammation, anti-bacteria, antitumor and et al. However …

Baicalin ameliorates experimental inflammatory bowel disease through polarization of macrophages to an M2 phenotype

W Zhu, Z Jin, J Yu, J Liang, Q Yang, F Li, X Shi… - International …, 2016 - Elsevier
Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders of the intestinal tract.
Baicalin, originally isolated from the root of the Chinese herb Huangqin (Scutellaria …

[HTML][HTML] Baicalin alleviates TNBS‑induced colitis by inhibiting PI3K/AKT pathway activation

L Zhu, H Shen, PQ Gu, YJ Liu… - Experimental and …, 2020 - spandidos-publications.com
Inflammatory bowel diseases (IBDs) are chronic immunological disorders of the intestinal
tract characterized by persistent inflammation. Baicalin, a type of flavonoid, has exhibited a …

[HTML][HTML] Therapeutic effect of the natural compounds baicalein and baicalin on autoimmune diseases

J Xu, J Liu, G Yue, M Sun, J Li… - Molecular Medicine …, 2018 - spandidos-publications.com
A series of natural compounds have been implicated to be useful in regulating the
pathogenesis of various autoimmune diseases. The present study demonstrated that the …

[HTML][HTML] Effects of baicalin in CD4+ CD29+ T cell subsets of ulcerative colitis patients

FY Yu, SG Huang, HY Zhang, H Ye… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To evaluate the role of baicalin in ulcerative colitis (UC) with regard to the CD4+ CD29+
T helper cell, its surface markers and serum inflammatory cytokines. METHODS: Flow …