Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression
S Egloff, D O'Reilly, RD Chapman, A Taylor… - Science, 2007 - science.org
RNA polymerase II (Pol II) transcribes genes that encode proteins and noncoding small
nuclear RNAs (snRNAs). The carboxyl-terminal repeat domain (CTD) of the largest subunit …
nuclear RNAs (snRNAs). The carboxyl-terminal repeat domain (CTD) of the largest subunit …
[PDF][PDF] Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes
The carboxy-terminal domain (CTD) of the large subunit of RNA polymerase II (Pol II)
comprises multiple heptapeptide repeats of the consensus Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6 …
comprises multiple heptapeptide repeats of the consensus Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6 …
Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7
RD Chapman, M Heidemann, TK Albert, R Mailhammer… - Science, 2007 - science.org
RNA polymerase II is distinguished by its large carboxyl-terminal repeat domain (CTD),
composed of repeats of the consensus heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 …
composed of repeats of the consensus heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 …
Expression of human snRNA genes from beginning to end
S Egloff, D O'Reilly, S Murphy - Biochemical Society …, 2008 - portlandpress.com
In addition to protein-coding genes, mammalian pol II (RNA polymerase II) transcribes
independent genes for some non-coding RNAs, including the spliceosomal U1 and U2 …
independent genes for some non-coding RNAs, including the spliceosomal U1 and U2 …
[HTML][HTML] The integrator complex recognizes a new double mark on the RNA polymerase II carboxyl-terminal domain
S Egloff, SA Szczepaniak, M Dienstbier, A Taylor… - Journal of Biological …, 2010 - ASBMB
The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (pol II)
comprises multiple tandem repeats of the heptapeptide Tyr 1-Ser 2-Pro 3-Thr 4-Ser 5-Pro 6 …
comprises multiple tandem repeats of the heptapeptide Tyr 1-Ser 2-Pro 3-Thr 4-Ser 5-Pro 6 …
[HTML][HTML] A 10 residue motif at the C‐terminus of the RNA pol II CTD is required for transcription, splicing and 3′ end processing
N Fong, G Bird, M Vigneron, DL Bentley - The EMBO journal, 2003 - embopress.org
Abstract The RNA polymerase II C‐terminal heptad repeat domain (CTD) is essential for
normal transcription and co‐transcriptional processing of mRNA precursors. The …
normal transcription and co‐transcriptional processing of mRNA precursors. The …
Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD
A Emili, M Shales, S McCracken, W Xie, PW Tucker… - Rna, 2002 - cambridge.org
The carboxyl-terminal domain (CTD) of the largest subunit of eukaryotic RNA polymerase II
(pol II) plays an important role in promoting steps of pre-mRNA processing. To identify …
(pol II) plays an important role in promoting steps of pre-mRNA processing. To identify …
Regulation of expression of human RNA polymerase II-transcribed snRNA genes
J Guiro, S Murphy - Open biology, 2017 - royalsocietypublishing.org
In addition to protein-coding genes, RNA polymerase II (pol II) transcribes numerous genes
for non-coding RNAs, including the small-nuclear (sn) RNA genes. snRNAs are an important …
for non-coding RNAs, including the small-nuclear (sn) RNA genes. snRNAs are an important …
The pol II CTD: new twists in the tail
J Zaborowska, S Egloff, S Murphy - Nature structural & molecular …, 2016 - nature.com
The C-terminal domain (CTD) of the large subunit of RNA polymerase (pol) II comprises
conserved heptad repeats, and post-translational modification of the CTD regulates …
conserved heptad repeats, and post-translational modification of the CTD regulates …
Gene-specific RNA polymerase II phosphorylation and the CTD code
Phosphorylation of the RNA polymerase (Pol) II C-terminal domain (CTD) repeats (1-
YSPTSPS-7) is coupled to transcription and may act as a'code'that controls mRNA synthesis …
YSPTSPS-7) is coupled to transcription and may act as a'code'that controls mRNA synthesis …