Stem cells have been widely assumed to be capable of replacing lost or damaged cells in a
number of diseases, including Parkinson's disease (PD), in which neurons of the substantia …

The ability to differentiate neural stem cells (NSCs) into dopamine neurons is fundamental to
their role in cell replacement therapies for neurodegenerative disorders such as Parkinson's …

Neural stem cells (NSC) have been shown to migrate towards damaged areas, produce
trophic factors, and replace lost cells in ways that might be therapeutic for Parkinson's …

Cell therapy has attracted considerable interest as a promising therapeutic alternative for
patients with Parkinson's disease (PD). Clinical studies have shown that grafted fetal neural …

Although evidence of damage-directed neural stem cell (NSC) migration has been well-
documented in the rodent, to our knowledge it has never been confirmed or quantified using …

A cell-based therapy for the replacement of dopaminergic neurons has been a long-term
goal in Parkinson's disease research. Here, we show that autologous engraftment of A9 …

Neural stem cells (NSCs) possess high potencies of self-renewal and neuronal
differentiation. We explored here whether transplantation of human NSCs cloned by v-myc …

Dopamine (DA) neurons derived from human embryonic stem cells (hESCs) are a promising
unlimited source of cells for cell replacement therapy in Parkinson's disease (PD). A number …

Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by a
progressive and extensive loss of dopaminergic (DA) neurons in the substantia nigra pars …

Parkinson's disease is characterized by the loss of dopaminergic neurons in the substantia
nigra. Attempted replacement of these neurons by stem cells has proved inconclusive. Bone …