Mutation N501Y in RBD of Spike Protein Strengthens the Interaction between COVID-19 and its Receptor ACE2
ABSTRACT SARS-CoV-2 is spreading around the world for the past year. Enormous efforts
have been taken to understand its mechanism of transmission. It is well established now that …
have been taken to understand its mechanism of transmission. It is well established now that …
N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2
SARS-CoV-2 has been spreading around the world for the past year. Recently, several
variants such as B. 1.1. 7 (alpha), B. 1.351 (beta), and P. 1 (gamma), which share a key …
variants such as B. 1.1. 7 (alpha), B. 1.351 (beta), and P. 1 (gamma), which share a key …
Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: Similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism
H Othman, Z Bouslama, JT Brandenburg… - Biochemical and …, 2020 - Elsevier
The spread of COVID-19 caused by the SARS-CoV-2 outbreak has been growing since its
first identification in December 2019. The publishing of the first SARS-CoV-2 genome made …
first identification in December 2019. The publishing of the first SARS-CoV-2 genome made …
Molecular mechanism of the N501Y mutation for enhanced binding between SARS-CoV-2's spike protein and human ACE2 receptor
Abstract Coronavirus disease 2019 (COVID-19) has been an ongoing global pandemic for
over a year. Recently, an emergent SARS-CoV-2 variant (B. 1.1. 7) with an unusually large …
over a year. Recently, an emergent SARS-CoV-2 variant (B. 1.1. 7) with an unusually large …
[HTML][HTML] Insilico study on the effect of SARS-CoV-2 RBD hotspot mutants' interaction with ACE2 to understand the binding affinity and stability
J Verma, N Subbarao - Virology, 2021 - Elsevier
The fall of 2020 brought several new variants of SARS-CoV-2 circulating across the globe,
and the steadily increasing COVID-19 cases are responsible for the emergence of these …
and the steadily increasing COVID-19 cases are responsible for the emergence of these …
Interactions of angiotensin-converting enzyme-2 (ACE2) and SARS-CoV-2 spike receptor-binding domain (RBD): a structural perspective
Abstract Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has
caused millions of infections and deaths worldwide since its discovery in late 2019 in …
caused millions of infections and deaths worldwide since its discovery in late 2019 in …
Evolutionary and structural analysis elucidates mutations on SARS-CoV2 spike protein with altered human ACE2 binding affinity
S Chakraborty - Biochemical and biophysical research communications, 2021 - Elsevier
The recognition of ACE2 by the receptor-binding domain (RBD) of spike protein mediates
host cell entry. The objective of the work is to identify SARS-CoV2 spike variants that …
host cell entry. The objective of the work is to identify SARS-CoV2 spike variants that …
V367F mutation in SARS-CoV-2 spike RBD emerging during the early transmission phase enhances viral infectivity through increased human ACE2 receptor binding …
J Ou, Z Zhou, R Dai, J Zhang, S Zhao, X Wu… - Journal of …, 2021 - Am Soc Microbiol
The current pandemic of COVID-19 is caused by a novel coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 spike protein receptor …
respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 spike protein receptor …
Binding interactions between receptor-binding domain of spike protein and human angiotensin converting enzyme-2 in omicron variant
The emergence of new SARS-CoV-2 Omicron variant of concern (OV) has exacerbated the
COVID-19 pandemic because of a large number of mutations in the spike protein …
COVID-19 pandemic because of a large number of mutations in the spike protein …
Key residues of the receptor binding domain in the spike protein of SARS-CoV-2 mediating the interactions with ACE2: a molecular dynamics study
The widespread coronavirus disease 2019 (COVID-19) has been declared a global health
emergency. As one of the most important targets for antibody and drug developments, the …
emergency. As one of the most important targets for antibody and drug developments, the …
相关搜索
- sars cov n501y mutation
- sars cov spike protein
- spike protein n501y mutation
- receptor ace2 n501y mutation
- receptor ace2 spike protein
- covid 19 mutation n501y
- spike ace2 interaction force
- interaction force n501y mutation
- covid 19 spike protein
- spike protein enzyme 2
- spike protein binding interactions
- sars cov receptor ace2
- binding interactions enzyme 2
- spike protein human angiotensin
- molecular mechanism n501y mutation
- spike protein molecular mechanism