Stem cell characteristics in prostate cancer cell lines

MJ Pfeiffer, JA Schalken - European urology, 2010 - Elsevier
BACKGROUND: Recent studies indicate the presence of a small, stem-like cell population in
several human cancers that is crucial for the tumour (re) population. OBJECTIVE: Six …

Evaluation of the frequency of putative prostate cancer stem cells in primary and metastatic prostate cancer

CL Eaton, M Colombel, G van der Pluijm… - The …, 2010 - Wiley Online Library
BACKGROUND Tumour cells with a stem cell‐like phenotype have recently been identified
in prostate tumors and it has been suggested that this population may be responsible for the …

Isolation and enrichment of PC-3 prostate cancer stem-like cells using MACS and serum-free medium

X Sheng, Z Li, DL Wang, WB Li, Z Luo… - Oncology …, 2013 - spandidos-publications.com
Prostate cancer stem-like cells (PCSLCs) are considered to be the 'seed'of prostate cancer.
The aim of this study was to confirm that the PC‑3 cells, which we isolated and enriched from …

Effective enrichment of prostate cancer stem cells from spheres in a suspension culture system

X Fan, S Liu, F Su, Q Pan, T Lin - Urologic Oncology: Seminars and Original …, 2012 - Elsevier
BACKGROUND: Stem-like prostate cancer cells are also called prostate cancer stem cells
(PrCSCs). These rare cells are supposed to be highly tumorigenic and to be involved in …

Prostate cell cultures as in vitro models for the study of normal stem cells and cancer stem cells

J Miki, JS Rhim - Prostate cancer and prostatic diseases, 2008 - nature.com
Current existing therapies for prostate cancer eradicate the majority of cells within a tumor.
However, most patients with advanced cancer still progress to androgen-independent …

Prospective identification of tumorigenic prostate cancer stem cells

AT Collins, PA Berry, C Hyde, MJ Stower, NJ Maitland - Cancer research, 2005 - AACR
Existing therapies for prostate cancer eradicates the bulk of cells within a tumor. However,
most patients go on to develop androgen-independent disease that remains incurable by …

Tumorspheres derived from prostate cancer cells possess chemoresistant and cancer stem cell properties

L Zhang, M Jiao, L Li, D Wu, K Wu, X Li, G Zhu… - Journal of cancer …, 2012 - Springer
Abstract Purpose Prostate cancer (PCa) becomes lethal when cancer cells develop into
castration-resistant PCa, which remains incurable because of the poor understanding of …

The characterization of epithelial and stromal subsets of candidate stem/progenitor cells in the human adult prostate

JA Ceder, L Jansson, RA Ehrnström, L Rönnstrand… - european urology, 2008 - Elsevier
OBJECTIVES: Questions regarding the cell source and mechanisms in the initiation and
progression of prostate cancer are today still open for debate. Indeed, our knowledge …

CD49f is an efficient marker of monolayer-and spheroid colony-forming cells of the benign and malignant human prostate

H Yamamoto, JR Masters, P Dasgupta, A Chandra… - 2012 - journals.plos.org
Stem cells may play a role in the development and maintenance of proliferative diseases of
the prostate such as prostate cancer and benign prostatic hyperplasia. Cell membrane …

Searching for prostate cancer stem cells: markers and methods

B Sharpe, M Beresford, R Bowen, J Mitchard… - Stem Cell Reviews and …, 2013 - Springer
The cancer stem cell hypothesis postulates that a single stem-like cancer cell is able to
produce all cancer cell types found in a tumor. These cells are also thought to be the …