A coming of age story: Chlamydia in the post-genetic era

AJ Hooppaw, DJ Fisher - Infection and immunity, 2016 - Am Soc Microbiol
Chlamydia spp. are ubiquitous, obligate, intracellular Gram-negative bacterial pathogens
that undergo a unique biphasic developmental cycle transitioning between the infectious …

Emancipating Chlamydia: advances in the genetic manipulation of a recalcitrant intracellular pathogen

RJ Bastidas, RH Valdivia - Microbiology and Molecular Biology …, 2016 - Am Soc Microbiol
Chlamydia species infect millions of individuals worldwide and are important etiological
agents of sexually transmitted disease, infertility, and blinding trachoma. Historically, the …

[HTML][HTML] Transformation of Chlamydia: current approaches and impact on our understanding of chlamydial infection biology

M Rahnama, KA Fields - Microbes and infection, 2018 - Elsevier
The intonation “The king is dead, long live the king” aptly describes the state of Chlamydia
research. Genetic-based approaches are rapidly replacing correlative strategies to provide …

[PDF][PDF] Expanding the molecular toolkit for Chlamydia

K Hybiske - Cell host & microbe, 2015 - cell.com
Although historically a genetically intractable bacterium, Chlamydia is experiencing a
renaissance for molecular genetic manipulation. Two new studies published in Cell Host & …

Advances and obstacles in the genetic dissection of chlamydial virulence

JA Brothwell, MK Muramatsu, G Zhong, DE Nelson - Biology of Chlamydia, 2018 - Springer
Obligate intracellular pathogens in the family Chlamydiaceae infect taxonomically diverse
eukaryotes ranging from amoebae to mammals. However, many fundamental aspects of …

Chlamydia genomics: providing novel insights into chlamydial biology

NL Bachmann, A Polkinghorne, P Timms - Trends in microbiology, 2014 - cell.com
Chlamydiaceae are obligate intracellular pathogens that have successfully evolved to
colonize a diverse range of hosts. There are currently 11 described species of Chlamydia …

[HTML][HTML] Chlamydial infection from outside to inside

A Gitsels, N Sanders, D Vanrompay - Frontiers in Microbiology, 2019 - frontiersin.org
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic
developmental cycle. Specific interactions with the host cell are crucial for the bacteria's …

Molecular Genetic Analysis of Chlamydia Species

BS Sixt, RH Valdivia - Annual Review of Microbiology, 2016 - annualreviews.org
Species of Chlamydia are the etiologic agent of endemic blinding trachoma, the leading
cause of bacterial sexually transmitted diseases, significant respiratory pathogens, and a …

Forward and Reverse Genetic Analysis of Chlamydia

M Kędzior, RJ Bastidas - Chlamydia trachomatis: Methods and Protocols, 2019 - Springer
Chlamydia is a major etiological agent of human disease that affects millions of individuals
worldwide. Historically, our understanding of the mechanisms that contribute to its …

A minimal replicon enables efficacious, species-specific gene deletion in Chlamydia and extension of gene knockout studies to the animal model of infection using …

KA Fields, MD Bodero, KR Scanlon… - Infection and …, 2022 - Am Soc Microbiol
The genus Chlamydia consists of diverse, obligate intracellular bacteria that infect various
animals, including humans. Although chlamydial species share many aspects of the typical …