The size, elasticity, and integrityof the large arteries is determined by the smoothmuscle cells
(SMCs) of the tunica media and by the connective tissue matrix including collagen, elastin …

Julie H. Campbell and Gordon R. Campbell Page 1 The role of smooth muscle cells in
atherosclerosis Julie H. Campbell and Gordon R. Campbell Centre for Research in Vascular …

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In 1968, Professor Robert Wissler published a landmark review on the role of smooth
muscle cells in atherogenesis. He suggested that in future studies more attention should be …

For a general survey of the atherosclerotic process, the reader is referred to recent reviews.
34-37 In the early stages of the disease, smooth muscle cells migrate from the media to the …

Accumulating evidence indicates that there is really only one cell type in the artery media
and that it is a multifunctional cell in the sense that it fabricates or directs the fabrication of …

The initiation of atherosclerosis results from complex interactions of circulating factors and
various cell types in the vessel wall, including endothelial cells, lymphocytes, monocytes …

The formation of a fibrous cap made up of intimal smooth muscle cells and connective tissue
is part of an attempt by the vessel wall to encapsulate the toxic products accumulating in the …

REGULATION OF SMOOTH MUSCLE CELL (SMC) GROWTH: Accelerated growth of SMC
is known to play an integral role in atherosclerotic lesion formation as well as post …

The cellular composition of human atherosclerotic plaques was analyzed by immunologic
techniques. Plaques were removed from the internal carotid artery during surgery, and a …