[HTML][HTML] Comparative genomics of non-pseudomonal bacterial species colonising paediatric cystic fibrosis patients
KL Ormerod, NM George, JA Fraser, C Wainwright… - PeerJ, 2015 - peerj.com
The genetic disorder cystic fibrosis is a life-limiting condition affecting∼ 70,000 people
worldwide. Targeted, early, treatment of the dominant infecting species, Pseudomonas …
worldwide. Targeted, early, treatment of the dominant infecting species, Pseudomonas …
Genomic and functional characterization of longitudinal Pseudomonas aeruginosa isolates from young patients with cystic fibrosis
CE Chandler, CE Hofstaedter, TH Hazen… - Microbiology …, 2023 - Am Soc Microbiol
Individuals with cystic fibrosis (CF) suffer from frequent and recurring microbial airway
infections. The Gram-negative bacterium Pseudomonas aeruginosa is one of the most …
infections. The Gram-negative bacterium Pseudomonas aeruginosa is one of the most …
Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …
airways has shown inefficient eradication of the infecting bacteria, as well as previously …
Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients
Abstract Background Chronic infection with Pseudomonas aeruginosa is a major cause of
morbidity and mortality in cystic fibrosis (CF) patients, and a more complete understanding of …
morbidity and mortality in cystic fibrosis (CF) patients, and a more complete understanding of …
Evolutionary Genomics of Niche-Specific Adaptation to the Cystic Fibrosis Lung in Pseudomonas aeruginosa
JR Dettman, R Kassen - Molecular biology and evolution, 2021 - academic.oup.com
The comparative genomics of the transition of the opportunistic pathogen Pseudomonas
aeruginosa from a free-living environmental strain to one that causes chronic infection in the …
aeruginosa from a free-living environmental strain to one that causes chronic infection in the …
Genome evolution drives transcriptomic and phenotypic adaptation in Pseudomonas aeruginosa during 20 years of infection
SJT Wardell, J Gauthier, LW Martin… - Microbial …, 2021 - microbiologyresearch.org
The opportunistic pathogen Pseudomonas aeruginosa chronically infects the lungs of
patients with cystic fibrosis (CF). During infection the bacteria evolve and adapt to the lung …
patients with cystic fibrosis (CF). During infection the bacteria evolve and adapt to the lung …
Selective sweeps and parallel pathoadaptation drive Pseudomonas aeruginosa evolution in the cystic fibrosis lung
J Diaz Caballero, ST Clark, B Coburn, Y Zhang… - MBio, 2015 - Am Soc Microbiol
Pulmonary infections caused by Pseudomonas aeruginosa are a recalcitrant problem in
cystic fibrosis (CF) patients. While the clinical implications and long-term evolutionary …
cystic fibrosis (CF) patients. While the clinical implications and long-term evolutionary …
Long-Term Microevolution of Pseudomonas aeruginosa Differs between Mildly and Severely Affected Cystic Fibrosis Lungs
J Klockgether, N Cramer, S Fischer… - American journal of …, 2018 - atsjournals.org
Chronic airway infections with Pseudomonas aeruginosa determine morbidity in most
individuals with cystic fibrosis (CF). P. aeruginosa may persist for decades in CF lungs …
individuals with cystic fibrosis (CF). P. aeruginosa may persist for decades in CF lungs …
Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection
Abstract The Cystic Fibrosis (CF) lung harbors a complex, polymicrobial ecosystem, in which
Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly …
Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly …
Draft genomes of 12 host-adapted and environmental isolates of Pseudomonas aeruginosa and their positions in the core genome phylogeny
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen particularly
associated with the inherited disease cystic fibrosis (CF). Pseudomonas aeruginosa is well …
associated with the inherited disease cystic fibrosis (CF). Pseudomonas aeruginosa is well …