Healthy ageing can be defined as “the process of developing and maintaining the functional
ability that enables wellbeing in older age”. Functional ability (ie, the health-related attributes …

Abstract Introduction The World Health Organization has introduced the term 'intrinsic
capacity'(IC) as a marker of healthy ageing. However, controversy exists on the definition …

Objectives Intrinsic capacity is a composite of five domains that summarizes the physical and
mental capacities of an individual. Intrinsic capacity is increasing in relevance for adapting …

Objectives This study aims to address the knowledge gap and summarise the measurement
for intrinsic capacity for the five WHO domains across different populations. It specifically …

Frailty is a clinical condition characterized by the individual's increased vulnerability to
endogenous and exogenous stressors. It is determined by the reduction of homeostatic …

Abstract Background The World Health Organization has proposed a model of healthy aging
built around the concept of functional ability, comprising an individual's intrinsic capacity, the …

The global increase in the aging population is expected to result in a shift from disease-
centered to function-centered approaches in response to intensive aging. Thus, the World …

Objectives The concept of 'intrinsic capacity'(IC) offers a new way to approach another
concept, that of 'healthy aging'. The first objective of the present study was to assess the …

Objectives Intrinsic capacity (IC) was proposed by the WHO as a new concept for capturing
an individual's functional capacities across their lifetime. We aimed to investigate the …

Introduction This study aims to develop and validate an integrative intrinsic capacity (IC)
scoring system, to investigate its associations with a wide spectrum of biomarkers and to …