Toll-like receptors in immunity and inflammatory diseases: Past, present, and future
K Vijay - International immunopharmacology, 2018 - Elsevier
The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …
cope with various pathogens present in the vicinity of environmental surroundings inhabited …
Toll receptors: an expanding role in our understanding of human disease
JM Schuster, PS Nelson - Journal of Leukocyte Biology, 2000 - academic.oup.com
Toll receptor proteins in Drosophila are involved in establishing the dorsal-ventral axis in
embryogenesis as well as participating in the innate immune response to invading …
embryogenesis as well as participating in the innate immune response to invading …
Immunobiology of Toll‐like receptors: emerging trends
S Pandey, DK Agrawal - Immunology and Cell Biology, 2006 - Wiley Online Library
Toll‐like receptors (TLR), a family of evolutionarily conserved pathogen recognition
receptors, play pivotal role as primary sensors of invading pathogens. TLR identify …
receptors, play pivotal role as primary sensors of invading pathogens. TLR identify …
Toll‐like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes
Toll is a Drosophila gene essential for ontogenesis and antimicrobial resistance. Several
hortologues of Toll have been identified and cloned in vertebrates, namely Toll‐like …
hortologues of Toll have been identified and cloned in vertebrates, namely Toll‐like …
[HTML][HTML] A comparative review of toll-like receptor 4 expression and functionality in different animal species
C Vaure, Y Liu - Frontiers in immunology, 2014 - frontiersin.org
Toll-like receptors (TLRs) belong to the pattern recognition receptor (PRR) family, a key
component of the innate immune system. TLRs detect invading pathogens and initiate an …
component of the innate immune system. TLRs detect invading pathogens and initiate an …
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer
Since first being described in the fruit fly Drosophila melanogaster, Toll-like receptors (TLRs)
have proven to be of great interest to immunologists and investigators interested in the …
have proven to be of great interest to immunologists and investigators interested in the …
RETRACTED: Expression and function of Toll-like receptor on T cells
D Xu, M Komai-Koma, FY Liew - Cellular Immunology, 2005 - Elsevier
Toll is the founder of a group of pattern recognition receptors, which play a critical role in the
innate immunity in Drosophila. At least 13 distinct Toll-like receptors (TLRs), recognising …
innate immunity in Drosophila. At least 13 distinct Toll-like receptors (TLRs), recognising …
Critical roles of Toll-like receptors in host defense
T Kaisho, S Akira - Critical Reviews™ in Immunology, 2000 - dl.begellhouse.com
Drosophila Toll is involved not only in dorsoventral patterning of embryos but also in
immune responses to microbial infection. Several Toll-like receptors (TLRs) have also been …
immune responses to microbial infection. Several Toll-like receptors (TLRs) have also been …
Potential therapeutic targets for inflammation in toll-like receptor 4 (TLR4)-mediated signaling pathways
Inflammation is set off when innate immune cells detect infection or tissue injury. Tight
control of the severity, duration, and location of inflammation is an absolute requirement for …
control of the severity, duration, and location of inflammation is an absolute requirement for …
Toll-like receptors as targets for immune disorders
B Keogh, AE Parker - Trends in Pharmacological Sciences, 2011 - cell.com
Since the identification of the first Toll-like receptor (TLR) in humans in 1997, understanding
of the molecular basis for innate immunity has increased significantly. The TLR family and …
of the molecular basis for innate immunity has increased significantly. The TLR family and …