The phytochemical diversity of commercial Cannabis in the United States

CJ Smith, D Vergara, B Keegan, N Jikomes - PLoS one, 2022 - journals.plos.org
The legal status of Cannabis is changing, fueling an increasing diversity of Cannabis-
derived products. Because Cannabis contains dozens of chemical compounds with potential …

Chemical composition of commercial cannabis

DS Wishart, M Hiebert-Giesbrecht… - Journal of agricultural …, 2024 - ACS Publications
Cannabis is widely used for medicinal and recreational purposes. As a result, there is
increased interest in its chemical components and their physiological effects. However …

Interplay between chemistry and morphology in medical cannabis (Cannabis sativa L.)

N Bernstein, J Gorelick, S Koch - Industrial Crops and Products, 2019 - Elsevier
Despite the long history of cannabis use, the chemical and physiological state of the plants
have not sufficiently been addressed due to legal restrictions. Hundreds of secondary …

Cannabinoids from Cannabis sativa L.: A New Tool Based on HPLC–DAD–MS/MS for a Rational Use in Medicinal Chemistry

M Protti, V Brighenti, MR Battaglia… - ACS medicinal …, 2019 - ACS Publications
Cannabis sativa L. represents one of the most widely used source of drugs and drugs of
abuse worldwide. Its biologically active compounds are mainly cannabinoids, including Δ9 …

The cannabinoid content of legal cannabis in Washington state varies systematically across testing facilities and popular consumer products

N Jikomes, M Zoorob - Scientific reports, 2018 - nature.com
The majority of adults in the US now have state-legal access to medical or recreational
cannabis products, despite their federal prohibition. Given the wide array of …

Cannabis sativa bioactive compounds and their extraction, separation, purification, and identification technologies: An updated review

Y Liu, HY Liu, SH Li, W Ma, DT Wu, HB Li… - TrAC Trends in …, 2022 - Elsevier
Cannabis sativa (C. sativa) has become a worldwide plant because of its multiple bioactive
compounds with a wide range of health benefits for humans. Notably, some cannabinoid …

Secondary metabolites profiled in cannabis inflorescences, leaves, stem barks, and roots for medicinal purposes

D Jin, K Dai, Z Xie, J Chen - Scientific reports, 2020 - nature.com
Cannabis research has historically focused on the most prevalent cannabinoids. However,
extracts with a broad spectrum of secondary metabolites may have increased efficacy and …

Leaner and greener analysis of cannabinoids

EM Mudge, SJ Murch, PN Brown - Analytical and bioanalytical chemistry, 2017 - Springer
There is an explosion in the number of labs analyzing cannabinoids in marijuana (Cannabis
sativa L., Cannabaceae) but existing methods are inefficient, require expert analysts, and …

Quantitative determination and validation of 17 cannabinoids in cannabis and hemp using liquid chromatography-tandem mass spectrometry

G McRae, JE Melanson - Analytical and bioanalytical chemistry, 2020 - Springer
The increase in production of cannabis for medical and recreational purposes in recent
years has led to a corresponding increase in laboratories performing cannabinoid analysis …

Development and validation of a GC-FID method for the quantitation of 20 different acidic and neutral cannabinoids

W Gul, EA Ibrahim, SW Gul, I Shahzadi… - Planta …, 2023 - thieme-connect.com
For decades, Cannabis sativa had been illegal to sell or consume around the world,
including in the United States. However, in light of the recent 2018 Farm Bill and the …