Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial

Ö Friberg, R Svedjeholm, B Söderquist… - The Annals of thoracic …, 2005 - Elsevier
BACKGROUND: Sternal wound infections remain a major cause of morbidity after cardiac
surgery. Vancomycin is often the only effective antibiotic available for their treatment but its …

[HTML][HTML] Gentamicin-collagen sponge reduces sternal wound complications after heart surgery: a controlled, prospectively randomized, double-blind study

C Schimmer, M Özkur, B Sinha, J Hain, A Gorski… - The Journal of thoracic …, 2012 - Elsevier
OBJECTIVE: Prophylactic retrosternal placement of a gentamicin-collagen sponge has been
the subject of several recent clinical studies and is a matter of controversy. The present study …

Incidence, microbiological findings, and clinical presentation of sternal wound infections after cardiac surgery with and without local gentamicin prophylaxis

Ö Friberg, R Svedjeholm, J Källman… - European Journal of …, 2007 - Springer
Sternal wound infection (SWI) is a serious complication after cardiac surgery. In a previous
randomized controlled trial, the addition of local collagen-gentamicin in the sternal wound …

Prophylaxis of sternal wound infections with gentamicin-collagen implant: randomized controlled study in cardiac surgery

AM Eklund, M Valtonen, KA Werkkala - Journal of Hospital Infection, 2005 - Elsevier
Postoperative infections may lead to prolonged hospital stay and increased morbidity,
mortality and hospital costs, especially in heart surgery. Finding new means to prevent …

Effect of an implantable gentamicin-collagen sponge on sternal wound infections following cardiac surgery: a randomized trial

E Bennett-Guerrero, TB Ferguson, M Lin, J Garg… - Jama, 2010 - jamanetwork.com
Context Despite the routine use of prophylactic systemic antibiotics, sternal wound infection
still occurs in 5% or more of cardiac surgical patients and is associated with significant …

[HTML][HTML] Gentamicin collagen sponges for the prevention of sternal wound infection: a meta-analysis of randomized controlled trials

MN Mavros, PK Mitsikostas, VG Alexiou… - The Journal of thoracic …, 2012 - Elsevier
OBJECTIVE: The study objective was to determine whether the application of gentamicin
collagen sponges reduces sternal wound infections in patients undergoing cardiac surgery …

[HTML][HTML] Gentamicin-collagen sponge reduces the risk of sternal wound infections after heart surgery: meta-analysis

M Kowalewski, W Pawliszak, K Zaborowska… - The Journal of thoracic …, 2015 - Elsevier
Objectives Sternal wound infections are serious postoperative complications that increase
the length of hospital stay and healthcare costs. The benefit of implantable gentamicin …

Collagen-gentamicin implant for prevention of sternal wound infection; long-term follow-up of effectiveness

Ö Friberg, LG Dahlin, J Källman… - … and thoracic surgery, 2009 - academic.oup.com
In a previous randomized controlled trial (LOGIP trial) the addition of local collagen-
gentamicin reduced the incidence of postoperative sternal wound infections (SWI) compared …

Comparison of clinical and economic outcomes of two antibiotic prophylaxis regimens for sternal wound infection in high-risk patients following coronary artery bypass …

K Dhadwal, S Al-Ruzzeh, T Athanasiou, M Choudhury… - Heart, 2007 - heart.bmj.com
Objective: Prospective studies show a 10% incidence of sternal wound infection (SWI) after
90 days of follow-up, compared with infection rates of 5% reported by the National …

Prevention of deep sternal wound infection in cardiac surgery: a literature review

RJ Vos, BP Van Putte, GTL Kloppenburg - Journal of Hospital Infection, 2018 - Elsevier
Background Deep sternal wound infection (DSWI) is a dreaded complication of cardiac
surgery with considerable consequences in terms of mortality, morbidity and treatment costs …