LAP, a transcriptional activator, and LIP, a transcriptional repressor, are translated from a
single mRNA species by using two AUGs within the same reading frame. These two proteins …

During postnatal liver development, LAP (NF‐IL‐6, C/EBP beta) expression and hepatocyte
proliferation are mutually exclusive. In addition to transactivating liver‐specific genes, LAP …

A gene, encoding a liver-enriched transcriptional activator protein (LAP) has been isolated.
LAP is a 32-kD protein that stimulates the transcription of chimeric genes containing albumin …

The CCAAT/enhancer-binding protein (C/EBP) alpha is a leucine zipper protein that is
preferentially expressed in certain cell types, such as adipocytes and hepatocytes. Here we …

A novel mammalian regulatory system was created by using the Escherichia coli lac
repressor. The lac repressor was converted into a mammalian transcriptional activator by …

We report on the identification of a nuclear protein that serves as a dominant-negative
inhibitor of the transcription factors C/EBP and LAP. A 32P-labeled LAP DNA-binding and …

LAP (NF-IL6 or C/EBP beta), is a liver transcriptional activator protein that confers liver-
specific gene expression. Because LAP has a characteristic phosphoacceptor sequence for …

In vertebrates, the mRNAs encoding ribosomal proteins, as well as other proteins implicated
in translation, are characterized by a 5′-untranslated region (5′-UTR), including a stretch …

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers a stress
response program that protects cells early in the response and can lead to apoptosis during …

Abstract LAP/C/EBPβ is a member of the C/EBP family of transcription factors and is involved
in hepatocyte-specific gene expression. Recently we showed that, besides its …