Background: Migraine is a common type of primary headache with disabling brain
dysfunction. It has been found that pituitary adenylate cyclase activating polypeptide …

Pituitary adenylate cyclase activating peptide (PACAP) can be found in the trigeminal (TG)
and the spenopalatine ganglia (SPG), and in the trigeminocervical complex. In the SPG it is …

Background Pituitary adenylate cyclase-activating polypeptide (PACAP) is a multipotent
neuropeptide widely distributed in the trigeminovascular system (TVS) and higher brain …

Pituitary adenylate cyclase activating peptide (PACAP) is found in human trigeminocervical
complex and can trigger migraine. PACAP levels were measured using a sensitive …

Background Pituitary adenylate cyclase-activating polypeptide (PACAP) is associated with
migraine phase; however, whether PACAP levels could be used to distinguish between …

Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors are widely
distributed at different levels of the pain-processing pathway. Its action at the peripheral …

Background Pituitary adenylate cyclase-activating polypeptide (PACAP) plays several
important roles in vasodilation, neurotransmission, neuromodulation and neurotrophy, as …

Background Several neurotransmitters are expressed in the neurons of the trigeminal
ganglion. One such signalling molecule is the pituitary adenylate cyclase-activating peptide …

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a naturally occurring
neuropeptide found in both the central and peripheral nervous systems of vertebrates …

Aims Chronic migraine (CM) is a common neurological disorder with complex pathogenesis.
Evidence suggests that pituitary adenylate cyclase-activating peptide (PACAP) induces …