Pilot scale production of poly (3-hydroxybutyrate-co-4-hydroxybutyrate) biopolymers with high molecular weight and elastomeric properties

KH Huong, MJ Azuraini, NA Aziz, AAA Amirul - Journal of bioscience and …, 2017 - Elsevier
Highlights•Reproducibility of P (3HB-co-4HB) with high molecular weight and elastomeric
properties was studied.•Sufficient oxygen supply during fermentation was found important in …

Surface-Modified Highly Biocompatible Bacterial-poly(3-hydroxybutyrate-co-4-hydroxybutyrate): A Review on the Promising Next-Generation Biomaterial

JM Chai, TSM Amelia, GK Mouriya, K Bhubalan… - Polymers, 2020 - mdpi.com
Polyhydroxyalkanoates (PHAs) are bacteria derived bio-based polymers that are
synthesised under limited conditions of nutritional elements with excess carbon sources …

Interactions between a poly (3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) terpolyester and human keratinocytes

Y Ji, XT Li, GQ Chen - Biomaterials, 2008 - Elsevier
A new member of polyhydroxyalkanoates (PHA) family, namely, a terpolyester abbreviated
as PHBVHHx consisting of 3-hydroxybutyrate (HB), 3-hydroxyvalerate (HV) and 3 …

Recent developments in the synthesis of poly (hydroxybutyrate) based biocomposites

ZA Raza, S Noor, S Khalil - Biotechnology Progress, 2019 - Wiley Online Library
Abstract Poly (hydroxybutyrate)(PHB) has become an attractive biomaterial in research and
development for past few years. It is natural bio‐based aliphatic polyester produced by many …

The properties of poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) and its applications in tissue engineering

Q Yang, J Wang, S Zhang, X Tang… - Current stem cell …, 2014 - ingentaconnect.com
Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate)(PHBHHx) is a member of the
polyhydroxyalkanoate (PHA) family. It is the designation of molecules consisting of random …

Effect of composition of poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) on growth of fibroblast and osteoblast

YW Wang, F Yang, Q Wu, Y Cheng, HF Peter, J Chen… - Biomaterials, 2005 - Elsevier
Films made of poly (3-hydroxybutyrate)(PHB), poly (3-hydroxybutyrate-co-3-
hydroxyhexanoate)(PHBHHx) consisting of 5%, 12% and 20% hydroxyhexanoate (HHx) …

Application of microbial polyesters-polyhydroxyalkanoates as tissue engineering materials

GQ Chen, Q Wu, YW Wang, Z Zheng - Key Engineering Materials, 2005 - Trans Tech Publ
Poly (hydroxybutyrate-co-hydroxyhexanoate)(PHBHHx) has improved mechanical
properties over the existing PHA and our results have shown that PHBHHx has better …

Studies on bone marrow stromal cells affinity of poly (3-hydroxybutyrate-co-3-hydroxyhexanoate)

M Yang, S Zhu, Y Chen, Z Chang, G Chen, Y Gong… - Biomaterials, 2004 - Elsevier
The objective of this study is to investigate the biocompatibility of poly (3-hydroxybutyrate-co-
3-hydroxyhexanoate)(PHBHHx) with bone marrow stromal cells in vitro. The adsorption of …

Responses in vivo to purified poly(3‐hydroxybutyrate‐co‐3‐hydroxyvalerate) implanted in a murine tibial defect model

CKA Wu, AR Pettit, S Toulson… - … Research Part A: An …, 2009 - Wiley Online Library
Effective bone biomaterials provide structural support for bone regeneration and elicit
minimal inflammatory or toxic effects in vivo. Poly (3‐hydroxybutyrate‐co‐3 …

Synthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) with high 4HB composition and PHA content using 1,4-butanediol and 1,6-hexanediol for medical …

H Norhafini, L Thinagaran, K Shantini… - Journal of polymer …, 2017 - Springer
Abstract Poly (3-hydroxybutyrate-co-4-hydroxybutyrate)[P (3HB-co-4HB)] with high 4HB
monomer harbors enhanced biocompatibility and mechanical properties, which are useful …