Thymus independent stimulator cells in the mixed lymphocyte reaction

MR Harrison - The Journal of Immunology, 1973 - journals.aai.org
The proliferative response of allogeneic lymphocytes cultured together, the mixed
lymphocyte reaction (MLR), has been widely used as an in vitro correlate of the antigen …

Serologically defined and lymphocyte-defined components of the major histocompatibility complex in the mouse

FH Bach, MB Widmer, ML Bach, J Klein - The Journal of Experimental …, 1972 - rupress.org
The mixed leukocyte culture (MLC) test is an in vitro model of the recognition phase of the
homograft response. For the most part, activation in MLC is dependent on differences of the …

In Vitro Secondary MLR: III: Hybrid Histocompatibility Determinants

CG Fathman, T Watanabe, A Augustin - The Journal of Immunology, 1978 - journals.aai.org
With cells obtained from long-term mixed lymphocyte culture (MLC) we have demonstrated
hybrid histocompatibility determinants that are recognized as mixed lymphocyte reaction …

Ia antigens are the stimulating determinants in the syngeneic mixed lymphocyte reaction

ED Johnson, CJ Krco, CS David - Transplantation, 1982 - journals.lww.com
The murine syngeneic mixed lymphocyte reaction (sMLR) is a T cell proliferative response to
self-antigens on non-T stimulator cells. The nature and specificity of the stimulating antigens …

Synergism between subpopulations of thymus-derived cells mediating the proliferative and effector phases of the mixed lymphocyte reaction

L Cohen, ML Howe - … of the National Academy of Sciences, 1973 - National Acad Sciences
The mixed lymphocyte reaction is characterized by proliferation and generation of
specifically cytotoxic effector lymphocytes. These two phases of the mixed lymphocyte …

[引用][C] The MLC reaction: Dilemma of divergent specificity of induction and effector function

E Möller - Tissue Antigens, 1973 - Wiley Online Library
Lymphoid cells from two different individuals mixed under in uitro culture conditions mutually
stimulate each other to blast transformation, and increased protein, RNA and DNA synthesis …

The MLR test in the mouse

T Meo - immunological methods, 1979 - Elsevier
Publisher Summary This chapter discusses the mixed lymphocyte reaction (MLR) test in
mouse. The immunobiology of histocompatibility has found a fundamental in vitro tool in the …

MLR-R and MLR-S gene products are expressed on different lymphoid cells

J BROCHIER - Transplantation, 1977 - journals.lww.com
The role of human B and T lymphocytes in the mixed lymphocyte reaction (MLR) was
investigated using T-and B-enriched populations obtained either by centrifugation of E …

Helper cells in the autologous mixed lymphocyte reaction. III. Production of helper factor (s) distinct from interleukin 2.

JA Wolos, JB Smith - The Journal of experimental medicine, 1982 - rupress.org
In normal mice, the autologous mixed lymphocyte reaction (AMLR) can activate helper T
cells that, in the presence of hapten-modified syngeneic cells, can induce a hapten-specific …

Specific positive selection of lymphocytes reactive to strong histocompatibility antigens

JC Howard, DB Wilson - The Journal of Experimental Medicine, 1974 - rupress.org
Selected populations of thymus-derived (T) rat lymphocytes having specific immunological
reactivity to chosen histocompatibility (H) alloantigens are found among the cellular products …