In Vitro and In Vivo Metabolite Identification Studies for the New Synthetic Opioids Acetylfentanyl, Acrylfentanyl, Furanylfentanyl, and 4-Fluoro-Isobutyrylfentanyl

S Watanabe, S Vikingsson, M Roman, H Green… - The AAPS Journal, 2017 - Springer
New fentanyl analogs have recently emerged as new psychoactive substances and have
caused numerous fatalities worldwide. To determine if the new analogs follow the same …

Clinical toxicology of newer recreational drugs

SL Hill, SHL Thomas - Clinical toxicology, 2011 - Taylor & Francis
Introduction. Novel synthetic 'designer'drugs with stimulant, ecstasy-like (entactogenic)
and/or hallucinogenic properties have become increasingly popular among recreational …

A case report on potential postmortem redistribution of furanyl fentanyl and 4-ANPP

F Freni, S Pezzella, C Vignali, M Moretti, S Cisini… - Forensic Science …, 2019 - Elsevier
Fatal intoxications due to accidental or voluntary intake of synthetic opioids represent an
actual emerging issue. We report a case where we have analyzed furanyl fentanyl and its …

The growing problem of new psychoactive substances (NPS)

BK Madras - … of New Psychoactive Substances (NPS) The Science …, 2017 - Springer
The term “new psychoactive substances”(NPS) can be defined as individual drugs in pure
form or in complex preparations that are not scheduled under the Single Convention on …

Opioid toxicity

D Dolinak - Academic forensic pathology, 2017 - journals.sagepub.com
In recent years, there has been a substantial increase in opioid use and abuse, and in
opioid-related fatal overdoses. The increase in opioid use has resulted at least in part from …

Fentanyl-related deaths: demographics, circumstances, and toxicology of 112 cases

GL Henderson - Journal of forensic sciences, 1991 - asmedigitalcollection.asme.org
Since 1979, the potent narcotic analgesic fentanyl and its analogs have been synthesized in
clandestine laboratories and sold as heroin substitutes. At least 112 overdose deaths have …

A fatality involving furanylfentanyl and MMMP, with presumptive identification of three MMMP metabolites in urine

C Nash, D Butzbach, P Stockham, T Scott… - Journal of analytical …, 2019 - academic.oup.com
The prevalence of new psychoactive substances (NPS) on the illicit drug market continues to
grow, with new analogs being routinely synthesized. Routes of administration for these …

[HTML][HTML] The novel psychoactive substances epidemic: A scientometric perspective

MJY Neoh, A Carollo, M Lim, O Corazza… - Addiction …, 2023 - Elsevier
The unprecedented proliferation of novel psychoactive substances (NPS) in the illicit drug
market has been a public health concern since their emergence in the 2000s. Their …

Fatal intoxications associated with the designer opioid AH-7921

R Kronstrand, G Thelander, D Lindstedt… - Journal of analytical …, 2014 - academic.oup.com
Abstract AH-7921 (3, 4-dichloro-N-[(1-dimethylamino) cyclohexylmethyl] benzamide) is a
designer opioid with∼ 80% of morphine's µ-agonist activity. Over a 6-month period, we …

Next generation of novel psychoactive substances on the horizon–A complex problem to face

JB Zawilska, D Andrzejczak - Drug and Alcohol Dependence, 2015 - Elsevier
Background The last decade has seen a rapid and continuous growth in the availability and
use of novel psychoactive substances (NPS) across the world. Although various products …