HIV type 1 drug resistance patterns among patients failing first and second line antiretroviral therapy in Nairobi, Kenya
Background The ever-expanding rollout of antiretroviral therapy in poor resource settings
without routine virological monitoring has been accompanied with development of drug …
without routine virological monitoring has been accompanied with development of drug …
Rates of virological suppression and drug resistance in adult HIV-1-positive patients attending primary healthcare facilities in KwaZulu-Natal, South Africa
Abstract Background KwaZulu-Natal (KZN) Province in South Africa has the highest HIV
disease burden in the country, with an estimated population prevalence of 24.7%. A pilot …
disease burden in the country, with an estimated population prevalence of 24.7%. A pilot …
Virological failure after 1 year of first-line ART is not associated with HIV minority drug resistance in rural Cameroon
A Zoufaly, J Jochum, R Hammerl… - Journal of …, 2015 - academic.oup.com
Objectives The aim of this study was to describe clinical and virological outcomes in therapy-
naive HIV-1-positive patients treated in a routine ART programme in rural Cameroon …
naive HIV-1-positive patients treated in a routine ART programme in rural Cameroon …
High viral load and multidrug resistance due to late switch to second-line regimens could be a major obstacle to reach the 90-90-90 UNAIDS objectives in sub …
E Guichet, A Aghokeng, L Serrano, G Bado… - AIDS Research and …, 2016 - liebertpub.com
In the context of lifelong antiretroviral treatment (ART) as early as possible and to end the
HIV/AIDS epidemic as a public health treat by 2030, it is important to evaluate the potential …
HIV/AIDS epidemic as a public health treat by 2030, it is important to evaluate the potential …
Virologic versus immunologic monitoring and the rate of accumulated genotypic resistance to first-line antiretroviral drugs in Uganda
SJ Reynolds, H Sendagire, K Newell… - BMC infectious …, 2012 - Springer
Background Viral load monitoring (VLM) to identify individuals failing antiretroviral therapy
(ART) is not widely available in resource-limited settings. We compared the genotypic …
(ART) is not widely available in resource-limited settings. We compared the genotypic …
Accumulation of drug resistance and loss of therapeutic options precede commonly used criteria for treatment failure in HIV-1 subtype-C-infected patients
RE Barth, SC Aitken, H Tempelman… - Antiviral …, 2012 - journals.sagepub.com
Background Virological monitoring is essential to identify antiretroviral treatment (ART)
failure, but not widely available. Here, accumulation of resistance and consequences for …
failure, but not widely available. Here, accumulation of resistance and consequences for …
Viremia and drug resistance among HIV-1 patients on antiretroviral treatment: a cross-sectional study in Soweto, South Africa
Z El-Khatib, AM Ekstrom, J Ledwaba, L Mohapi… - Aids, 2010 - journals.lww.com
Background: We assessed risk factors for viremia and drug resistance among long-term
recipients of antiretroviral therapy (ART) in South Africa. Methods: In 2008, we conducted a …
recipients of antiretroviral therapy (ART) in South Africa. Methods: In 2008, we conducted a …
Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya
K Steegen, S Luchters, K Dauwe, J Reynaerts… - AIDS research and …, 2009 - Springer
Access to antiretroviral therapy (ART) is increasing in resource-limited settings (RLS) and
can successfully reduce HIV-related morbidity and mortality. However, virologic failure and …
can successfully reduce HIV-related morbidity and mortality. However, virologic failure and …
Prevalence and characteristics of HIV drug resistance among antiretroviral treatment (ART) experienced adolescents and young adults living with HIV in Ndola …
S Miti, R Handema, L Mulenga, JK Mwansa… - PLoS …, 2020 - journals.plos.org
Background HIV drug resistance (HIVDR) poses a threat to the HIV epidemic control in
Zambia especially in sub-populations such as the 15–24 years where there is poor …
Zambia especially in sub-populations such as the 15–24 years where there is poor …
Prevalence and patterns of HIV drug resistance in patients with suspected virological failure in North-Western Tanzania
S Henerico, SG Mikasi, SE Kalluvya… - Journal of …, 2022 - academic.oup.com
Background More than 15 million people in sub-Saharan Africa receive ART. Treatment
failure is common, but the role of HIV drug resistance in treatment failure is largely unknown …
failure is common, but the role of HIV drug resistance in treatment failure is largely unknown …