[HTML][HTML] Accumulation of HIV-1 drug resistance in patients on a standard thymidine analogue-based first line antiretroviral therapy after virological failure: implications …

A De Luca, ZJ Sidumo, G Zanelli, NA Magid… - BMC infectious …, 2017 - Springer
Background We describe the accumulation of HIV-1 drug resistance and its effect on the
activity of next-line components in patients with virological failure (HIV-1 RNA> 1000 …

Prevalence of viral load suppression, predictors of virological failure and patterns of HIV drug resistance after 12 and 48 months on first-line antiretroviral therapy: a …

D Ssemwanga, J Asio, C Watera… - Journal of …, 2020 - academic.oup.com
Objectives We implemented the WHO cross-sectional survey protocol to determine rates of
HIV viral load (VL) suppression (VLS), and weighted prevalence, predictors and patterns of …

Antiretroviral treatment outcome in HIV‐1‐infected patients routinely followed up in capital cities and remote areas of Senegal, Mali and Guinea‐Conakry

AAM Diouara, HD Ndiaye, I Guindo… - Journal of the …, 2014 - Wiley Online Library
Introduction Access to antiretroviral treatment (ART) becomes more and more effective in
resource‐limited settings (RLS). However, this global effort would be even more profitable if …

HIV-1 drug resistance in antiretroviral-naive individuals in sub-Saharan Africa after rollout of antiretroviral therapy: a multicentre observational study

RL Hamers, CL Wallis, C Kityo, M Siwale… - The Lancet infectious …, 2011 - thelancet.com
Background There are few data on the epidemiology of primary HIV-1 drug resistance after
the roll-out of antiretroviral treatment (ART) in sub-Saharan Africa. We aimed to assess the …

HIV-1 drug resistance and third-line therapy outcomes in patients failing second-line therapy in Zimbabwe

C Chimbetete, D Katzenstein, T Shamu… - Open forum …, 2018 - academic.oup.com
Objectives To analyze the patterns and risk factors of HIV drug resistance mutations among
patients failing second-line treatment and to describe early treatment responses to …

Low rates of nucleoside reverse transcriptase inhibitor resistance in a well-monitored cohort in South Africa on antiretroviral therapy

CL Wallis, MA Papathanasopolous, M Fox… - Antiviral …, 2012 - journals.sagepub.com
Background The emergence of complex HIV-1 drug resistance mutations has been linked to
the duration of time patients are on a failing antiretroviral drug regimen. This study reports on …

[HTML][HTML] Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first-and second-line antiretroviral treatment …

GU Van Zyl, TF Liu, M Claassen, S Engelbrecht… - PloS one, 2013 - journals.plos.org
Objectives South Africa's national antiretroviral (ARV) treatment program expanded in 2010
to include the nucleoside reverse transcriptase (RT) inhibitors (NRTI) tenofovir (TDF) for …

Viraemia and HIV-1 drug resistance mutations among patients receiving antiretroviral treatment in Mozambique

F Maldonado, M Biot, F Roman… - Transactions of the …, 2009 - academic.oup.com
This study was conducted among individuals taking first-line antiretroviral treatment (ART)
for at least 12 months under programme conditions in Maputo, Mozambique in order to …

[HTML][HTML] High prevalence of pre-treatment and acquired HIV-1 drug resistance mutations among non-citizens living with HIV in Botswana

PT Mokgethi, WT Choga, D Maruapula… - Frontiers in …, 2024 - frontiersin.org
Background Approximately 30,000 non-citizens are living with HIV in Botswana, all of whom
as of 2020 are eligible to receive free antiretroviral treatment (ART) within the country. We …

HIV virological failure and drug resistance in a cohort of Tanzanian HIV-infected adults

C Hawkins, N Ulenga, E Liu, S Aboud… - Journal of …, 2016 - academic.oup.com
Objectives There are few data on ART failure rates and drug resistance from Tanzania,
where there is a wide diversity of non-B HIV subtypes. We assessed rates and predictors of …