[HTML][HTML] Virological failure, HIV-1 drug resistance, and early mortality in adults admitted to hospital in Malawi: an observational cohort study
A Gupta-Wright, K Fielding, JJ van Oosterhout… - The Lancet …, 2020 - thelancet.com
Background Antiretroviral therapy (ART) scale-up in sub-Saharan Africa combined with
weak routine virological monitoring has driven increasing HIV drug resistance. We …
weak routine virological monitoring has driven increasing HIV drug resistance. We …
HIV-1 drug resistance among Ugandan adults attending an urban out-patient clinic
A von Braun, C Sekaggya-Wiltshire… - JAIDS Journal of …, 2018 - journals.lww.com
Background: Little is known about prevalence of drug resistance among HIV-infected
Ugandans, a setting with over 15 years of public sector access to antiretroviral therapy (ART) …
Ugandans, a setting with over 15 years of public sector access to antiretroviral therapy (ART) …
[HTML][HTML] HIV-1 drug resistance testing is essential for heavily-treated patients switching from first-to second-line regimens in resource-limited settings: evidence from …
D Takou, J Fokam, G Teto, MM Santoro… - BMC infectious …, 2019 - Springer
Background With the phase-out of stavudine (d4T), change to first-line regimens with
zidovudine (AZT) or tenofovir (TDF) in resource-limited settings (RLS) might increase risks of …
zidovudine (AZT) or tenofovir (TDF) in resource-limited settings (RLS) might increase risks of …
[HTML][HTML] HIV-1 drug resistance in adults and adolescents on protease inhibitor-based antiretroviral therapy in KwaZulu-Natal Province, South Africa
Objectives In low–middle-income countries, increasing levels of HIV drug resistance
(HIVDR) on second-line protease inhibitor (PI)-based regimens are a cause for concern …
(HIVDR) on second-line protease inhibitor (PI)-based regimens are a cause for concern …
Risk of virological failure and drug resistance during first and second-line antiretroviral therapy in a 10-year cohort in Senegal: results from the ANRS 1215 cohort
P De Beaudrap, M Thiam, A Diouf… - JAIDS Journal of …, 2013 - journals.lww.com
Background: In 1998, Senegal launched one of Africa's first antiretroviral therapy (ART)
programs. Since then, the number of treated patients in Africa has substantially increased …
programs. Since then, the number of treated patients in Africa has substantially increased …
[HTML][HTML] Comparison of HIV drug resistance profiles across HIV-1 subtypes A and D for patients receiving a tenofovir-based and zidovudine-based first line regimens …
A Ayitewala, F Kyeyune, P Ainembabazi… - AIDS research and …, 2020 - Springer
Background Resistance to antiretroviral drugs is a major challenge among Human
Immunodeficiency Virus (HIV) positive patients receiving antiretroviral therapy (ART) …
Immunodeficiency Virus (HIV) positive patients receiving antiretroviral therapy (ART) …
Associations with virologic treatment failure in adults on antiretroviral therapy in South Africa
MI Datay, A Boulle, D Mant… - JAIDS Journal of Acquired …, 2010 - journals.lww.com
Objectives: Highly active antiretroviral therapy (HAART) has been available in government
facilities in the Western Cape Province of South Africa since 2001. We aimed to investigate …
facilities in the Western Cape Province of South Africa since 2001. We aimed to investigate …
A retrospective survey of HIV drug resistance among patients 1 year after initiation of antiretroviral therapy at 4 clinics in Malawi
N Wadonda-Kabondo, BL Hedt… - Clinical infectious …, 2012 - academic.oup.com
In 2004, Malawi began scaling up its national antiretroviral therapy (ART) program. Because
of limited treatment options, population-level surveillance of acquired human …
of limited treatment options, population-level surveillance of acquired human …
[HTML][HTML] Pre-treatment HIV-drug resistance associated with virologic outcome of first-line NNRTI-antiretroviral therapy: a cohort study in Kenya
IA Beck, M Levine, CJ McGrath, S Bii, RS Milne… - …, 2020 - thelancet.com
Background Pre-treatment HIV-drug-resistance (PDR) to WHO-recommended 1st-line non-
nucleoside reverse transcriptase inhibitors (NNRTI)-based antiretroviral treatment (ART) is …
nucleoside reverse transcriptase inhibitors (NNRTI)-based antiretroviral treatment (ART) is …
Emergence of multiclass drug–resistance in HIV-2 in antiretroviral-treated individuals in senegal: implications for hiv-2 treatment in resouce-limited West Africa
GS Gottlieb, NMD Badiane, SE Hawes… - Clinical Infectious …, 2009 - academic.oup.com
Background. The efficacy of various antiretroviral (ARV) therapy regimens for human
immunodeficiency virus type 2 (HIV-2) infection remains unclear. HIV-2 is intrinsically …
immunodeficiency virus type 2 (HIV-2) infection remains unclear. HIV-2 is intrinsically …