Diabetic myopathy, a less studied complication of diabetes, exhibits the clinical observations
characterized by a less muscle mass, muscle weakness and a reduced physical functional …

Objective This study was aimed to investigate the role of Toll-like receptor 4 (TLR4) in
advanced glycation end products (AGEs)-induced macrophage polarization toward M1 …

Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune
system and a state of chronic inflammation. The disease can cause life-threatening …

Attack by reactive oxygen intermediates, common to many kinds of cell/tissue injury, has
been implicated in the development of diabetic and other vascular diseases. Such oxygen …

Ageing-associated changes that affect articular tissues promote the development of
osteoarthritis (OA). Although ageing and OA are closely linked, they are independent …

Little is known about advanced glycation end products (AGEs) participation in glucose
homeostasis, a process in which skeletal muscle glucose transporter GLUT4 (Scl2a4 gene) …

Ligation of advanced glycation end products (AGEs) with their receptor (RAGE) plays an
important role in the development of various diabetes complications, including …

Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the
adult population. OA is primarily caused by trauma induced by an external force or by age …

Advanced glycation end-products (AGEs) are a heterogeneous group of compounds formed
by the Maillard chemical process of non-enzymatic glycation of free amino groups of …

Advanced glycation end products (AGEs) are harmful compounds generated by nonspecific
glycation of proteins and lipids. The accumulation of AGEs is associated with various …