Male infertility: the effect of natural antioxidants and phytocompounds on seminal oxidative stress

M Adewoyin, M Ibrahim, R Roszaman, ML Md Isa… - Diseases, 2017 - mdpi.com
Defective sperm function has been identified as the most common cause of infertility. The
objective of this study was to review recent findings on the effects of various antioxidants on …

Involvement of seminal leukocytes, reactive oxygen species, and sperm mitochondrial membrane potential in the DNA damage of the human spermatozoa

AM Lobascio, M De Felici, M Anibaldi, P Greco… - …, 2015 - Wiley Online Library
Measurement of reactive oxygen species (ROS) producing leukocytes in semen has been a
standard component of the semen analysis, but its true significance remains still unknown. In …

Relative impact of oxidative stress on male reproductive function

SC Sikka - Current medicinal chemistry, 2001 - ingentaconnect.com
Impairment of normal spermatogenesis and sperm function are the most common causes of
male factor infertility. Abnormal sperm function is difficult to evaluate and treat. There is a …

[HTML][HTML] Role of reactive oxygen species in the pathophysiology of human reproduction

A Agarwal, RA Saleh, MA Bedaiwy - Fertility and sterility, 2003 - Elsevier
OBJECTIVE: To summarize the role of reactive oxygen species (ROS) in the
pathophysiology of human reproduction. DESIGN: Review of literature. SETTING: Fertility …

Oxidative stress & male infertility

K Makker, A Agarwal, R Sharma - Indian Journal of Medical …, 2009 - journals.lww.com
The male factor is considered a major contributory factor to infertility. Apart from the
conventional causes for male infertility such as varicocoele, cryptorchidism, infections …

Oxidative versus reductive stress: a delicate balance for sperm integrity

N Sadeghi, G Boissonneault, M Tavalaee… - Systems biology in …, 2023 - Taylor & Francis
Despite the long-standing notion of “oxidative stress,” as the main mediator of many
diseases including male infertility induced by increased reactive oxygen species (ROS) …

Detection of apoptotic alterations in sperm in subfertile patients and their correlations with sperm quality

HM Shen, J Dai, SE Chia, A Lim… - Human Reproduction, 2002 - academic.oup.com
BACKGROUND: The aim of the present study was to define the effect of apoptosis on sperm
quality and function. METHODS: The apoptotic features in sperm were assessed in 60 …

The role of the natural antioxidant mechanism in sperm cells

A Kowalczyk - Reproductive sciences, 2022 - Springer
Molecular studies of the causes of male infertility revealed a significant contribution of
oxidative stress. When excessive amounts of reactive oxygen species (ROS) are produced …

[HTML][HTML] Sperm viability, apoptosis, and intracellular reactive oxygen species levels in human spermatozoa before and after induction of oxidative stress

RZ Mahfouz, SS du Plessis, N Aziz, R Sharma… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To investigate sperm viability, incidence of apoptosis, and intracellular basal
and induced reactive oxygen species (ROS) in sperm fractions. DESIGN: Prospective …

Oxidative stress and male infertility

S Bisht, M Faiq, M Tolahunase, R Dada - Nature Reviews Urology, 2017 - nature.com
DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm
function. High levels of oxidative stress result in damage to sperm DNA, RNA transcripts …