Sepsis can be seen as a PRR-mediated dysregulation of the immune system following
pathogen invasion in which a careful balance between inflammatory and anti-inflammatory …

Introduction: Sepsis is characterized by a dysregulated host response to infection. Sepsis-
associated morbidity/mortality demands concerted research efforts toward therapeutic …

Our understanding of sepsis and its resultant outcomes remains a paradox. On the one
hand, we know more about the pathophysiology of sepsis than ever before. However, this …

Sepsis is a syndrome related to severe infections. It is defined as the systemic host response
to microorganisms in previously sterile tissues and is characterized by end-organ …

Introduction Sepsis is a complex inflammatory disorder believed to originate from an
infection by any types of microbes and/or their products. It is the leading cause of death in …

Sepsis is a complex syndrome characterized by simultaneous activation of inflammation and
coagulation in response to microbial insult. These events manifest as systemic inflammatory …

Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …

Sepsis is defined as “a life‐threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection.” At present, sepsis continues to …

Sepsis ist eine lebensbedrohliche Komplikation schwerer Infektionen. Einhergehend mit
dem systemischen Entzündungssyndrom (SIRS) führt die Sepsis zum multiplem …

Sepsis remains the leading cause of death in most intensive care units. Advances in
understanding the immune response to sepsis provide the opportunity to develop more …