Mapping systemic inflammation and antibody responses in multisystem inflammatory syndrome in children (MIS-C)

CN Gruber, RS Patel, R Trachtman, L Lepow, F Amanat… - Cell, 2020 - cell.com
Initially, children were thought to be spared from disease caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). However, a month into the epidemic, a novel …

[HTML][HTML] Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children

A Ramaswamy, NN Brodsky, TS Sumida, M Comi… - Immunity, 2021 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening post-infectious
complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV-2 …

The immune landscape of SARS-CoV-2-associated Multisystem Inflammatory Syndrome in Children (MIS-C) from acute disease to recovery

E Syrimi, E Fennell, A Richter, P Vrljicak, R Stark, S Ott… - Iscience, 2021 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening disease
occurring several weeks after severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Multisystem inflammatory syndrome in children (MIS‐C) associated with 2019 novel coronavirus (SARS‐CoV‐2) infection

H Kest, A Kaushik, W DeBruin, M Colletti… - Case reports in …, 2020 - Wiley Online Library
We report three critically ill pediatric patients (aged 6–10 years), presenting with features of
multisystem inflammatory syndrome in children (MIS‐C) from April 4 to May 10, 2020, to a …

Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS–CoV-2

C Diorio, SE Henrickson, LA Vella… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Initial reports from the severe acute respiratory coronavirus 2 (SARS–CoV-
2) pandemic described children as being less susceptible to coronavirus disease 2019 …

The immunology of multisystem inflammatory syndrome in children with COVID-19

CR Consiglio, N Cotugno, F Sardh, C Pou, D Amodio… - Cell, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is typically very
mild and often asymptomatic in children. A complication is the rare multisystem inflammatory …

The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children

RA Porritt, A Binek, L Paschold… - The Journal of …, 2021 - Am Soc Clin Investig
Multisystem inflammatory syndrome in children (MIS-C) manifests as a severe and
uncontrolled inflammatory response with multiorgan involvement, occurring weeks after …

MIS-C: early lessons from immune profiling

LA Henderson, RSM Yeung - Nature Reviews Rheumatology, 2021 - nature.com
Multisystem inflammatory syndrome in children (MIS-C) is a rare complication of SARS-CoV-
2 infection that can result in serious illness in the paediatric population but our …

Multisystem inflammatory syndrome in US children and adolescents

LR Feldstein, EB Rose, SM Horwitz… - … England Journal of …, 2020 - Mass Medical Soc
Background Understanding the epidemiology and clinical course of multisystem
inflammatory syndrome in children (MIS-C) and its temporal association with coronavirus …

Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19

LA Vella, JR Giles, AE Baxter, DA Oldridge… - Science …, 2021 - science.org
Pediatric coronavirus disease 2019 (COVID-19) after SARS-CoV-2 infection is associated
with fewer hospitalizations and often milder disease than in adults. A subset of children …