Critical overview of the use of Ru (II) polypyridyl complexes as photosensitizers in one-photon and two-photon photodynamic therapy
Conspectus Photodynamic Therapy (PDT) is an emerging technique to treat certain types of
cancer, bacterial, fungal, and viral infections, and skin diseases. In past years, different …
cancer, bacterial, fungal, and viral infections, and skin diseases. In past years, different …
[HTML][HTML] Dual mode of cell death upon the photo-irradiation of a Ru II polypyridyl complex in interphase or mitosis
V Pierroz, R Rubbiani, C Gentili, M Patra, C Mari… - Chemical …, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) is an attractive, complementary medical technique to
chemotherapy. Among the different photosensitizers (PSs) employed, Ru (II) polypyridyl …
chemotherapy. Among the different photosensitizers (PSs) employed, Ru (II) polypyridyl …
Rationally designed long-wavelength absorbing Ru (II) polypyridyl complexes as photosensitizers for photodynamic therapy
J Karges, F Heinemann, M Jakubaszek… - Journal of the …, 2020 - ACS Publications
The utilization of photodynamic therapy (PDT) for the treatment of various types of cancer
has gained increasing attention over the last decades. Despite the clinical success of …
has gained increasing attention over the last decades. Despite the clinical success of …
Evaluation of the medicinal potential of two ruthenium (II) polypyridine complexes as one‐and two‐photon photodynamic therapy photosensitizers
Abstract Two [Ru (phen) 2dppz] 2+ derivatives (phen= 1, 10‐phenantroline, dppz= dipyrido
[3, 2‐a: 2′, 3′‐c] phenazine) with different functional groups on the dppz ligand [dppz‐7, 8 …
[3, 2‐a: 2′, 3′‐c] phenazine) with different functional groups on the dppz ligand [dppz‐7, 8 …
[HTML][HTML] Rationally designed ruthenium complexes for 1-and 2-photon photodynamic therapy
The use of photodynamic therapy (PDT) against cancer has received increasing attention
over recent years. However, the application of the currently approved photosensitizers (PSs) …
over recent years. However, the application of the currently approved photosensitizers (PSs) …
Synthesis, characterization, and biological evaluation of new Ru (II) polypyridyl photosensitizers for photodynamic therapy
Two Ru (II) polypyridyl complexes, Ru (DIP) 2 (bdt)(1) and [Ru (dqpCO2Me)(ptpy)]
2+(2)(DIP= 4, 7-diphenyl-1, 10-phenanthroline, bdt= 1, 2-benzenedithiolate, dqpCO2Me= 4 …
2+(2)(DIP= 4, 7-diphenyl-1, 10-phenanthroline, bdt= 1, 2-benzenedithiolate, dqpCO2Me= 4 …
DNA Intercalating RuII Polypyridyl Complexes as Effective Photosensitizers in Photodynamic Therapy
C Mari, V Pierroz, R Rubbiani, M Patra… - … A European Journal, 2014 - Wiley Online Library
Six substitutionally inert [RuII (bipy) 2dppz] 2+ derivatives (bipy= 2, 2′‐bipyridine, dppz=
dipyrido [3, 2‐a: 2′, 3′‐c] phenazine) bearing different functional groups on the dppz …
dipyrido [3, 2‐a: 2′, 3′‐c] phenazine) bearing different functional groups on the dppz …
Mechanisms of action of Ru (II) polypyridyl complexes in living cells upon light irradiation
The unique photophysical properties of Ru (II) polypyridyl complexes make them very
attractive candidates as photosensitisers in Photodynamic Therapy (PDT). However, to date …
attractive candidates as photosensitisers in Photodynamic Therapy (PDT). However, to date …
Increasing the π-expansive ligands in ruthenium (II) polypyridyl complexes: synthesis, characterization, and biological evaluation for photodynamic therapy …
MD Pozza, P Mesdom, A Abdullrahman… - Inorganic …, 2023 - ACS Publications
Lack of selectivity is one of the main issues with currently used chemotherapies, causing
damage not only to altered cells but also to healthy cells. Over the last decades …
damage not only to altered cells but also to healthy cells. Over the last decades …
Light-activated ruthenium complexes photobind DNA and are cytotoxic in the photodynamic therapy window
E Wachter, DK Heidary, BS Howerton… - Chemical …, 2012 - pubs.rsc.org
Incorporation of biquinoline ligands into Ru (II) polypyridyl complexes produces light-
activated systems that eject a ligand and photobind DNA after irradiation with visible and …
activated systems that eject a ligand and photobind DNA after irradiation with visible and …
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