Structurally simple osmium (II) polypyridyl complexes as photosensitizers for photodynamic therapy in the near infrared

A Mani, T Feng, A Gandioso, R Vinck… - Angewandte …, 2023 - Wiley Online Library
Five osmium (II) polypyridyl complexes of the general formula [Os (4, 7‐diphenyl‐1, 10‐
phenanthroline) 2L] 2+ were synthesized as photosensitizers for photodynamic therapy by …

[HTML][HTML] Development of novel tetrapyrrole structure photosensitizers for cancer photodynamic therapy

N Plekhova, O Shevchenko, O Korshunova… - Bioengineering, 2022 - mdpi.com
The effectiveness of photodynamic therapy (PDT) is based on the triad effects of
photosensitizer (PS), molecular oxygen and visible light on malignant tumors. Such complex …

New avenues in the design and potential application of metal complexes for photodynamic therapy

OJ Stacey, SJA Pope - Rsc Advances, 2013 - pubs.rsc.org
Photodynamic therapy (PDT) requires a photosensitizing agent, which can undergo visible
light activation, yielding reactive oxygen species and/or radical species. The key physical …

An estrogen receptor targeted ruthenium complex as a two-photon photodynamic therapy agent for breast cancer cells

X Zhao, M Li, W Sun, J Fan, J Du, X Peng - Chemical Communications, 2018 - pubs.rsc.org
In this study, we reported a tamoxifen modified Ru (II) polypyridyl complex (Ru-tmxf) as an
estrogen receptor (ER) targeted photosensitizer. Ru-tmxf displays enhanced cellular uptake …

A new heteroleptic ruthenium (II) polypyridyl complex with long‐wavelength absorption and high singlet‐oxygen quantum yield

QX Zhou, WH Lei, JR Chen, C Li… - … A European Journal, 2010 - Wiley Online Library
Ruthenium (II) polypyridyl complexes with long‐wavelength absorption and high singlet‐
oxygen quantum yield exhibit attractive potential in photodynamic therapy. A new …

[HTML][HTML] An azo dye for photodynamic therapy that is activated selectively by two-photon excitation

V Juvekar, CS Lim, DJ Lee, SJ Park, GO Song… - Chemical …, 2021 - pubs.rsc.org
Two-photon photodynamic therapy (TP-PDT) is a promising approach for the treatment of
cancer because of its better penetration depth and superior spatial selectivity. Here, we …

Bromo-substituted diketopyrrolopyrrole derivative with specific targeting and high efficiency for photodynamic therapy

Y Cai, Q Tang, X Wu, W Si, Q Zhang… - … Applied Materials & …, 2016 - ACS Publications
Novel photosensitizers with high reactive oxygen species generation and precise targeting
to tumors are crucial for photodynamic therapy (PDT). Here, a bromo-substituted …

[HTML][HTML] Research advances in the use of tetrapyrrolic photosensitizers for photodynamic therapy

ES Nyman, PH Hynninen - Journal of Photochemistry and Photobiology B …, 2004 - Elsevier
Photodynamic therapy (PDT) is a promising new treatment modality for several diseases,
most notably cancer. In PDT, light, O2, and a photosensitizing drug are combined to produce …

Photobiological activity of Ru (II) dyads based on (pyren-1-yl) ethynyl derivatives of 1, 10-phenanthroline

S Monro, J Scott, A Chouai, R Lincoln, R Zong… - Inorganic …, 2010 - ACS Publications
Several mononuclear Ru (II) dyads possessing 1, 10-phenanthroline-appended
pyrenylethynylene ligands were synthesized, characterized, and evaluated for their potential …

[HTML][HTML] New Ru (II) photocages operative with near-IR light: new platform for drug delivery in the PDT window

MH Al-Afyouni, TN Rohrabaugh, KF Al-Afyouni… - Chemical …, 2018 - pubs.rsc.org
A series of Ru (II) complexes bearing the tridentate 2, 6-di (quinolin-2-yl) pyridine (dqpy)
ligand were designed to undergo photoinduced ligand dissociation with red/near-IR light …