There has been an enormous interest to investigate impact of gut microbiota on host
physiology over the past decade. To further understand its role at organismal level, it is …

The microbiota is a heterogeneous ecosystem consisting of diverse microorganisms unique
to an individual, playing a crucial role in maintaining human body homeostasis. The …

Background Alterations in gut microbiota composition and bacterial metabolites have been
increasingly recognized to affect host metabolism and are at the basis of metabolic diseases …

Host sensing in the gut microbiota has been crucial in the regulation of intestinal
homeostasis. Although inflammatory bowel diseases (IBDs), multifactorial chronic …

Gut bacteria exert a variety of metabolic functions unavailable to the host and are
increasingly seen as a virtual organ located inside our gastrointestinal tract. Scattered in our …

Background The gut microbiota is associated with several of metabolic diseases, including
obesity and type 2 diabetes and affects host physiology through distinct mechanisms. The …

The microbial community of the gut conveys significant benefits to host physiology. A clear
relationship has now been established between gut bacteria and host metabolism in which …

There are more than 2 billion overweight and obese individuals worldwide, surpassing for
the first time, the number of people affected by undernutrition. Obesity and its comorbidities …

Highlights•The gut microbiota interacts with enteroendocrine cells.•SCFAs triggers gut
peptide secretion through GPR43-dependent and GPR41-dependent mechanisms.•The gut …

The gastrointestinal system is now considered the largest endocrine organ, highlighting the
importance of gut-derived peptides and metabolites in metabolic homeostasis. Gut peptides …