Matrix vesicles produced by osteoblast-like cells in culture become significantly enriched in proteoglycan-degrading metalloproteinases after addition of β …

DD Dean, Z Schwartz, L Bonewald, OE Muniz… - Calcified tissue …, 1994 - Springer
Matrix vesicles, media vesicles, and plasma membranes from three well-characterized,
osteoblast-like cells (ROS 17/2.8, MG-63, and MC-3T3-E1) were evaluated for their content …

Fibroblast growth factor-2 inhibits mineralization of osteoblast-like Saos-2 cells by inhibiting the functioning of matrix vesicles

C Liu, Y Cui, J Luan, X Zhou, Z Liu… - Drug Discoveries & …, 2014 - jstage.jst.go.jp
Summary Fibroblast growth factor-2 (FGF2) inhibits osteoblast mineralization, but the
mechanism by which it does so is not fully understood. Matrix vesicles (MVs) play an …

The first stage of transforming growth factor β1 activation is release of the large latent complex from the extracellular matrix of growth plate chondrocytes by matrix …

S Maeda, DD Dean, R Gomez, Z Schwartz… - Calcified tissue …, 2002 - Springer
Transforming growth factor beta-1 (TGF-β1) is secreted in a biologically inactive form and
stored in the extracellular matrix as a 290 kDa complex consisting of the mature TGF-βl …

[引用][C] Simulation of chondrogenesis and preosteogenesis in vitro

F Suzuki - Bone, 1985 - Elsevier

[HTML][HTML] Effects of BMP2 and VEGF165 on the osteogenic differentiation of rat bone marrow‑derived mesenchymal stem cells

Z Lin, JS Wang, L Lin, J Zhang… - Experimental and …, 2014 - spandidos-publications.com
Bone marrow‑derived mesenchymal stem cells (MSCs) are dominant seed cell sources for
bone regeneration. Bone morphogenetic proteins (BMPs) initiate cartilage and bone …

Matrix vesicles and mineralisation

A Kapustin - Bone Abstracts, 2014 - bone-abstracts.org
Vascular calcification is a ubiquitous pathology in the aged and diseased vasculature.
Recently we have focused on the earliest events in the calcification process and have …

Expression of BMPs in adult human osteophyte tissue

S Zoričić, I Marić, V Šantić, D Bobinac… - 1st Joint Meeting of the …, 2001 - croris.hr
Sažetak Osteoarthrisis is characterized by focal cartilage destruction and marked formation
of osteophytes. This study was performed on a series of 25 osteophytes removed from the …

The role of bone morphogens in human osteophyte formation

S Zoričić, I Marić, V Šantić, D Bobinac… - European Symposium on …, 2000 - croris.hr
Sažetak Apart from degenerative changes in osteoarthritis, formation of new cartilage and
bone occurs at the margin of articular surfaces, forming bone spurs, osteophytes. Bone …

Responsiveness of clonal limb bud cell lines to bone morphogenetic protein 2 reveals a sequential relationship between cartilage and bone cell phenotypes

V Rosen, J Nove, JJ Song, RS Thies… - Journal of Bone and …, 1994 - Wiley Online Library
There is growing evidence to suggest that BMPs are among the signals necessary to create
the embryonic skeleton, but how these regulatory molecules enter the pathways of …

Expression profiles of BMP-related molecules induced by BMP-2 or-4 in muscle-derived primary culture cells

Y Nakamura, S Wakitani, N Saito, K Takaoka - Journal of bone and …, 2005 - Springer
The formation of ectopic bone in muscle following the implantation of decalcified bone matrix
led to the search and eventual discovery of bone morphogenetic proteins (BMPs) in bone …