Nucleic acid molecules
M Fotin-Mleczek, K Fiedler, A Kowalczyk… - US Patent …, 2021 - Google Patents
The present invention provides novel artificial nucleic acid molecules encoding at least one
antigenic peptide or protein and at least one additional sequence preferably targeting the …
antigenic peptide or protein and at least one additional sequence preferably targeting the …
Artificial nucleic acid molecules
S Grund, T Schlake - US Patent 11,697,816, 2023 - Google Patents
The invention relates to an artificial nucleic acid molecule comprising at least one open
reading frame and at least one 3′-untranslated region element (3′-UTR element) …
reading frame and at least one 3′-untranslated region element (3′-UTR element) …
Artificial nucleic acid molecules for improved protein or peptide expression
A Thess - US Patent App. 16/920,701, 2020 - Google Patents
The invention relates to an artificial nucleic acid molecule comprising at least one 5′ UTR
element which is derived from a TOP gene, at least one open reading frame, and preferably …
element which is derived from a TOP gene, at least one open reading frame, and preferably …
Artificial nucleic acid molecules
T Schlake, S Grund - US Patent App. 15/755,739, 2018 - Google Patents
The invention relates to an artificial nucleic acid molecule comprising at least one open
reading frame and at least one 3′-untranslated region element (3′-UTR element) and/or …
reading frame and at least one 3′-untranslated region element (3′-UTR element) and/or …
Artificial nucleic acid molecules
S Grund, T Schlake - US Patent App. 15/540,610, 2018 - Google Patents
The invention relates to an artificial nucleic acid molecule comprising at least one open
reading frame and at least one 3′-untranslated region element (3′-UTR element) and/or …
reading frame and at least one 3′-untranslated region element (3′-UTR element) and/or …
Artificial nucleic acid molecules for improved protein or peptide expression
A Thess - US Patent 10,738,306, 2020 - Google Patents
The invention relates to an artificial nucleic acid molecule comprising at least one 5′ UTR
element which is derived from a TOP gene, at least one open reading frame, and preferably …
element which is derived from a TOP gene, at least one open reading frame, and preferably …
Vaccines comprising synthetic genes
JW Shiver, ME Davies, DC Freed, MA Liu… - US Patent …, 2003 - Google Patents
Synthetic polynucleotides comprising a DNA sequence encoding a peptide or protein are
provided. The DNA sequence of the synthetic polynucleotides comprise codons optimized …
provided. The DNA sequence of the synthetic polynucleotides comprise codons optimized …
Preparation and use of superior vaccines
B Roberts, S Shankara - US Patent App. 11/332,546, 2006 - Google Patents
This invention provides an isolated population of polynucle otides comprising or
corresponding to at least one poly nucleotide shown in Table 1 and their respective comple …
corresponding to at least one poly nucleotide shown in Table 1 and their respective comple …
Recombinant gene expression vectors and methods for use of same to enhance the immune response of a host to an antigen
D Carson, E Raz, M Roman - US Patent App. 10/402,100, 2003 - Google Patents
The invention consists of recombinant gene expression vectors and vaccines useful in
immunization of a host against an antigen and methods for use of such vectors and …
immunization of a host against an antigen and methods for use of such vectors and …
Recombinant gene expression vectors and methods for use of same to enhance the immune response of a host to an antigen
D Carson, E Raz, M Roman - US Patent App. 09/947,209, 2003 - Google Patents
The invention consists of recombinant gene expression vectors and vaccines useful in
immunization of a host against an antigen and methods for use of such vectors and …
immunization of a host against an antigen and methods for use of such vectors and …