It has been proposed that oxidant stress of cells in the lung is one of the underlying
mechanisms of particulate pollution-induced exacerbation of lung disease. Individuals who …

Epidemiologic studies have reported causal relationships between exposures to high
concentrations of ambient air particles (AAP) and increased morbidity in individuals with …

Adverse health effects of urban air pollution particulates may be attributable to particle
mediated oxidant stress and inflammation. Intracellular oxidant production in normal …

Epidemiologic data show that air pollution particulates cause adverse pulmonary health
effects, especially in individuals with preexisting lung disease. We sought to model in vitro …

A number of epidemiological studies have associated increased cardiopulmonary mortality
and hospital admissions with episodes of high particulate air pollution. Inhaled particles …

The mechanisms for increased cardiopulmonary disease in individuals exposed to
particulate air pollution are associated with fine and ultrafine particles that have a high …

The classic toxicology paradigm between exposure and response provides the justification
for accurate measurement of exposure to underpin good epidemiological studies aimed at …

Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …

The toxic effects of air pollution are widely documented. In recent years, however, there has
been an increasing interest in the study of the health effects of particulate matter (PM), a …

Following exposure to 2 ppm ozone for 4 hr, two distinct effects on rat lung inflammatory cell
oxidant generation were observed. TPA-and opsonized zymosan-stimulated O2• production …