Alzheimer's disease (AD) is an age-related neurodegenerative disease marked by a
progressive cognitive decline. Metabolic impairments are common hallmarks of AD, and …

Alzheimer's disease (AD) is a multifactorial age-related neurodegenerative disease that
today has no effective treatment to prevent or slow its progression. Neuroactive steroids …

Hormonal deficit in post-menopausal women has been proposed to be one risk factor in
Alzheimer's disease (AD) since two thirds of AD patients are women. However, large …

Translocator protein 18 kDa (TSPO) is located in the mitochondrial outer membrane and
plays an important role in steroidogenesis and cell survival. In the central nervous system …

Several studies have linked stress with Alzheimer's disease (AD) vulnerability; however, the
mechanism remains to be fully elucidated. In the current paper, we investigated the role of …

Studies performed with animals suggest neurosteroid involvement in neuroprotection.
However in humans, the role of neurosteroidogenesis in the regulation of degenerative …

Alzheimer's disease (AD) is the most prevalent aging-associated neurodegenerative
disease, with a higher incidence in women than men. There is evidence that sex hormone …

Alzheimer's disease (AD) is a neurodegenerative disease with a complex and progressive
pathological phenotype characterized first by hypometabolism and impaired mitochondrial …

Amyloid precursor protein (APP) mis‐processing and aberrant tau hyperphosphorylation are
causally related to the pathogenesis and neurodegenerative processes that characterize …

Translocator protein 18 kDa (TSPO) is a mitochondrial protein located in the outer
membrane and involved in cholesterol translocation, a prerequisite for steroid biosynthesis …