The innate immune system recognises a wide spectrum of pathogens without a need for
prior exposure. The main cells responsible are monocytes, macrophages, dendritic cells …

Members of the Toll-like receptor (TLR) family probably play a fundamental role in pathogen
recognition and activation of innate immunity. The present study used a systematic approach …

Toll is the founder of a group of pattern recognition receptors, which play a critical role in the
innate immunity in Drosophila. At least 13 distinct Toll-like receptors (TLRs), recognising …

Toll-like receptors (TLRs) are key regulators of the innate and adaptive immune response to
bacterial, viral, and fungal pathogens. To date, 10 human TLRs and 13 mouse TLRs have …

Toll-like receptors (TLRs) play important roles in host resistance to infections, but also act as
mediators of pathologies in autoimmunity, septic shock, metabolic disease and cancer. TLRs …

Inflammation is set off when innate immune cells detect infection or tissue injury. Tight
control of the severity, duration, and location of inflammation is an absolute requirement for …

Toll-like receptors (TLRs) belong to the pattern recognition receptor (PRR) family, a key
component of the innate immune system. TLRs detect invading pathogens and initiate an …

Toll receptor proteins in Drosophila are involved in establishing the dorsal-ventral axis in
embryogenesis as well as participating in the innate immune response to invading …

Pattern recognition receptors (PRR) play an important roll in immediate responses to
different conserved molecules produced by microbes. In this paper we describe the cloning …

Members of the Toll-like receptor (TLR) family mediate dorsoventral patterning and cellular
adhesion in insects as well as immune responses to microbial products in both insects and …