[HTML][HTML] Engineering strategies for customizing extracellular vesicle uptake in a therapeutic context
A Esmaeili, M Alini, M Baghaban Eslaminejad… - Stem Cell Research & …, 2022 - Springer
Extracellular vesicles (EVs) are advanced therapeutic strategies that can be used to
efficiently treat diseases. Promising features of EVs include their innate therapeutic …
efficiently treat diseases. Promising features of EVs include their innate therapeutic …
Good things come in small packages: Overcoming challenges to harness extracellular vesicles for therapeutic delivery
Extracellular vesicles (EVs) hold great promise as potential therapeutic carriers. EVs are
biologically active, intrinsically transporting cargo between cells. Moreover, they can be …
biologically active, intrinsically transporting cargo between cells. Moreover, they can be …
Extracellular vesicles: Emerging anti-cancer drugs and advanced functionalization platforms for cancer therapy
M Wu, M Wang, H Jia, P Wu - Drug Delivery, 2022 - Taylor & Francis
Increasing evidences show that unmodified extracellular vesicles (EVs) derived from various
cells can effectively inhibit the malignant progression of different types of tumors by …
cells can effectively inhibit the malignant progression of different types of tumors by …
Extracellular vesicles for improved tumor accumulation and penetration
N Bie, T Yong, Z Wei, L Gan, X Yang - Advanced drug delivery reviews, 2022 - Elsevier
Extracellular vesicles (EVs), including microparticles and exosomes, have emerged as
potential tools for tumor targeting delivery during the past years. Recently, mass of strategies …
potential tools for tumor targeting delivery during the past years. Recently, mass of strategies …
[HTML][HTML] Targeted therapy using engineered extracellular vesicles: principles and strategies for membrane modification
Q Liu, D Li, X Pan, Y Liang - Journal of nanobiotechnology, 2023 - Springer
Abstract Extracellular vesicles (EVs) are 30–150 nm membrane-bound vesicles naturally
secreted by cells and play important roles in intercellular communication by delivering …
secreted by cells and play important roles in intercellular communication by delivering …
[HTML][HTML] Extracellular vesicles as an efficient and versatile system for drug delivery
Despite the recent advances in drug development, the majority of novel therapeutics have
not been successfully translated into clinical applications. One of the major factors hindering …
not been successfully translated into clinical applications. One of the major factors hindering …
Generation, purification and engineering of extracellular vesicles and their biomedical applications
Extracellular vesicles (EVs), derived from cell membranes, demonstrate the potential to be
excellent therapeutics and drug carriers. Although EVs are promising, the process to …
excellent therapeutics and drug carriers. Although EVs are promising, the process to …
[HTML][HTML] Exploring interactions between extracellular vesicles and cells for innovative drug delivery system design
Extracellular vesicles (EVs) are submicron cell-secreted structures containing proteins,
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …
New approaches in extracellular vesicle engineering for improving the efficacy of anti-cancer therapies
Cancer is a disease that evolves continuously with unpredictable outcomes. Although
conventional chemotherapy can display significant antitumor effects, the lack of specificity …
conventional chemotherapy can display significant antitumor effects, the lack of specificity …
[HTML][HTML] Extracellular vesicles as drug transporters
M Nowak, J Górczyńska, K Kołodzińska… - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer-delimited particles. According to their size and
synthesis pathway, EVs can be classified into exosomes, ectosomes (microvesicles), and …
synthesis pathway, EVs can be classified into exosomes, ectosomes (microvesicles), and …