Extracellular vesicles as delivery systems at nano-/micro-scale

P Fu, J Zhang, H Li, M Mak, W Xu, Z Tao - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) have shown significant promises as nano-/micro-size carriers in
drug delivery and bioimaging. With more characteristics of EVs explored through …

[HTML][HTML] EVs and bioengineering: from cellular products to engineered nanomachines

S Villata, M Canta, V Cauda - International journal of molecular sciences, 2020 - mdpi.com
Extracellular vesicles (EVs) are natural carriers produced by many different cell types that
have a plethora of functions and roles that are still under discovery. This review aims to be a …

[HTML][HTML] Extracellular vesicles: The next generation in gene therapy delivery

R Cecchin, Z Troyer, K Witwer, KV Morris - Molecular Therapy, 2023 - cell.com
Extracellular vesicles (EVs) are esteemed as a promising delivery vehicle for various genetic
therapeutics. They are relatively inert, non-immunogenic, biodegradable, and …

[PDF][PDF] Engineered mammalian and bacterial extracellular vesicles as promising nanocarriers for targeted therapy

H Liu, Z Geng, J Su - Extracell Vesicles Circ Nucleic Acids, 2022 - f.oaes.cc
Extracellular vesicles (EVs), which are nanocarriers with phospholipid bilayer structures
released by most cells, play a key role in regulating physiological and pathological …

[HTML][HTML] Dosing extracellular vesicles

D Gupta, AM Zickler, S El Andaloussi - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) are natural nanoparticles containing biologically active
molecules. They are important mediators of intercellular communication and can be …

Stem cell-derived extracellular vesicles for cancer therapy and tissue engineering applications

CS Lee, M Lee, K Na, HS Hwang - Molecular Pharmaceutics, 2023 - ACS Publications
Recently, stem cells and their secretomes have attracted great attention in biomedical
applications, particularly extracellular vesicles (EVs). EVs are secretomes of cells for cell-to …

[HTML][HTML] Biogenesis and delivery of extracellular vesicles: harnessing the power of EVs for diagnostics and therapeutics

J Yu, S Sane, JE Kim, S Yun, HJ Kim, KB Jo… - Frontiers in Molecular …, 2024 - frontiersin.org
Extracellular vesicles (EVs) are membrane-enclosed particles secreted by a variety of cell
types. These vesicles encapsulate a diverse range of molecules, including proteins, nucleic …

[HTML][HTML] Extracellular vesicle-embedded materials

Y Ma, S Brocchini, GR Williams - Journal of Controlled Release, 2023 - Elsevier
Extracellular vesicles (EVs) are small membrane-bound vesicles released by cells. EVs are
emerging as a promising class of therapeutic entity that could be adapted in formulation due …

Modularized extracellular vesicles: the dawn of prospective personalized and precision medicine

SC Tao, SC Guo, CQ Zhang - Advanced Science, 2018 - Wiley Online Library
Extracellular vesicles (EVs) are ubiquitous nanosized membrane vesicles consisting of a
lipid bilayer enclosing proteins and nucleic acids, which are active in intercellular …

Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper

T Lener, M Gimona, L Aigner, V Börger… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …