Inflammatory bowel diseases (IBD) comprise a distinct set of clinical symptoms resulting
from chronic or relapsing immune activation and corresponding inflammation within the …

Over the past decade a major hypothesis has emerged for the etiopathogenesis of
inflammatory bowel disease (IBD). This hypothesis proposes that IBD represents a …

Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory condition of the
intestines that is clinically heterogenous. The cause (s) of IBD are currently unknown but the …

Inflammatory bowel disease (IBD) is a group of idiopathic, chronic and relapsing
inflammatory conditions of the gastrointestinal tract. Familial and epidemiological studies …

Inflammatory bowel disease (IBD) is an abnormal inflammatory response within the gut to a
trigger that has yet to be identified. The family history in many patients, especially those with …

Inflammatory bowel disease (IBD) is an idiopathic disease thought to be caused by a
dysregulated immune response to host intestinal microflora. The role of genetic factors is …

Inflammatory bowel diseases are characterized by chronic intestinal inflammation at different
sites. Data from animal models as well as human patients including gene-association …

The mechanisms that maintain intestinal homeostasis despite constant exposure of the gut
surface to multiple environmental antigens and to billions of microbes have been scrutinized …

Inflammatory bowel diseases are a set of complex and chronic disorders that arise in
genetically predisposed individuals due to a lack of tolerance to the gut microflora. Although …

Advancements in human genetics now poise the field to illuminate the pathophysiology of
complex genetic disease. In particular, genome-wide association studies (GWAS) have …