Amorphous solid dispersions (ASDs) are commonly manufactured using spray-drying
processes. The product quality can be decisively influenced by the choice of process …

Driven by the new trend to build quality into products and reducing empiricism, small-scale
screening techniques have been frequently used to evaluate, thermodynamic of drug …

The evaluation of drug–polymer miscibility in the early phase of drug development is
essential to ensure successful amorphous solid dispersion (ASD) manufacturing. This work …

Understanding and prevention of unwanted changes of a pharmaceutical formulation during
the production process is part of the critical requirements for the successful approval of a …

Spray drying is widely used in the manufacturing of amorphous solid dispersion (ASD)
systems due to its fast drying rate, enabling kinetic trapping of the drug in amorphous form …

The use of amorphous solid dispersions (ASDs) in commercial drug products has increased
in recent years due to the large number of poorly soluble drugs in the pharmaceutical …

Solid amorphous dispersions are frequently used to improve the solubility and, thus, the
bioavailability of poorly soluble active pharmaceutical ingredients (APIs). Spray-drying, a …

Amorphous solid dispersions (ASDs) are often used for formulating poorly water-soluble
active pharmaceutical ingredients (APIs). In an ASD, the amorphous API is embedded in a …

Amorphous solid dispersion (ASD) has been well known as a potential strategy to improve
the bioavailability and dissolution performance of poorly water-soluble drugs. The primary …

Purpose To present a new screening methodology intended to be used in the early
development of spray-dried amorphous solid dispersions. Methods A model that combines …