G ENERALLY, the purpose of assessing thyroid function in a given patient is to determine
his metabolic status. In patients with systemic nonthyroidal illness, as well as in those …

Multiple alterations in the serum concentration of the iodothyronines have been recognized
in patients with systemic non-thyroidal illnesses (NTI). Most prominent are the low serum 3 …

Abnormalities of thyroid hormone concentrations are seen commonly in a wide variety of
nonthyroidal illnesses, resulting in low triiodothyronine, total thyroxine, and thyroid …

In a prospective study, we assessed the role of thyrotropin in the development of the low-
thyroxine state that is associated with severe illness. We measured the serum thyrotropin …

The reported failure of serum TSH to rise inresponse to the low serum T3 ofsevere systemic
illness may bedue to the known stress inhibition of TSH secretion. We thereforemeasured …

This article briefly summarizes thyroid function alterations generally seen in the euthyroid
sick syndrome, provides an overview of specific thyroidal adaptations during several clinical …

We studied variables known to change with thyroid hormone status in 18 patients with
subclinical hypothyroidism before and during treatment with thyroxine in a dose sufficient to …

This study reports in vitro and in vivo parameters of T4 metabolism in patients with critical
nonthyroidal (illnesses who were selected because of serum total T4 values less than 3µg/dl …

Background: A “sick euthyroid” syndrome occurs in patients with severe decompensated
chronic heart failure (CHF) and other chronic illnesses and is related to adverse prognosis …

Thyroid hormone abnormalities are common in critically ill patients. For over three decades,
a mild form of these abnormalities has been described in patients with several diseases …