Volatile organic compounds in breath as markers of lung cancer: a cross-sectional study

M Phillips, K Gleeson, JMB Hughes, J Greenberg… - The Lancet, 1999 - thelancet.com
Background Many volatile organic compounds (VOCs), principally alkanes and benzene
derivatives, have been identified in breath from patients with lung cancer. We investigated …

Comparison of volatile organic compounds from lung cancer patients and healthy controls—Challenges and limitations of an observational study

K Schallschmidt, R Becker, C Jung… - Journal of breath …, 2016 - iopscience.iop.org
This paper outlines the design and performance of an observational study on the profiles of
volatile organic compounds (VOCs) in the breath of 37 lung cancer patients and 23 healthy …

Detection of lung cancer with volatile markers in the breath

M Phillips, RN Cataneo, ARC Cummin, AJ Gagliardi… - Chest, 2003 - Elsevier
Study objectives To evaluate volatile organic compounds (VOCs) in the breath as tumor
markers in lung cancer. Alkanes and monomethylated alkanes are oxidative stress products …

[HTML][HTML] Exhaled breath analysis for lung cancer

AG Dent, TG Sutedja, PV Zimmerman - Journal of thoracic disease, 2013 - ncbi.nlm.nih.gov
Early diagnosis of lung cancer results in improved survival compared to diagnosis with more
advanced disease. Early disease is not reliably indicated by symptoms. Because …

Quantitative breath analysis of volatile organic compounds of lung cancer patients

G Song, T Qin, H Liu, GB Xu, YY Pan, FX Xiong, KS Gu… - Lung cancer, 2010 - Elsevier
Due to state-of-art analytical techniques, non-invasive exhaled volatile organic compounds
(VOCs) analysis has become a potential method for early diagnosis of lung cancer. We …

A review of exhaled breath: a key role in lung cancer diagnosis

D Marzorati, L Mainardi, G Sedda… - Journal of breath …, 2019 - iopscience.iop.org
One of the main causes of the high mortality rate in lung cancer is the late-stage tumor
detection. Early diagnosis is therefore essential to increase the chances of obtaining an …

Prediction of lung cancer using volatile biomarkers in breath

M Phillips, N Altorki, JHM Austin… - Cancer …, 2007 - content.iospress.com
Background: Normal metabolism generates several volatile organic compounds (VOCs) that
are excreted in the breath (eg alkanes). In patients with lung cancer, induction of high-risk …

[HTML][HTML] Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study

D Poli, P Carbognani, M Corradi, M Goldoni… - Respiratory …, 2005 - Springer
Background Non-invasive diagnostic strategies aimed at identifying biomarkers of lung
cancer are of great interest for early cancer detection. The aim of this study was to set up a …

Comparative analyses of volatile organic compounds (VOCs) from patients, tumors and transformed cell lines for the validation of lung cancer-derived breath markers

W Filipiak, A Filipiak, A Sponring… - Journal of breath …, 2014 - iopscience.iop.org
Breath analysis for the purpose of non-invasive diagnosis of lung cancer has yielded
numerous candidate compounds with still questionable clinical relevance. To arrive at …

A study of the volatile organic compounds exhaled by lung cancer cells in vitro for breath diagnosis

X Chen, F Xu, Y Wang, Y Pan, D Lu… - … Journal of the …, 2007 - Wiley Online Library
BACKGROUND. The specific volatile organic compounds (VOCs) exhaled by lung cancer
cells in the microenvironment are the source biomarkers of lung cancer and also serve as …